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PSD-95 Antibody (6G6) is a mouse monoclonal IgG2a light chain antibody that detects PSD-95 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PSD-95, a member of the membrane-associated guanylate kinase (MAGUK) family, plays a crucial role in the organization of synaptic signaling complexes in neurons, which is vital for proper synaptic function and plasticity. PSD-95 is primarily located at the postsynaptic density of excitatory synapses, where PSD-95 interacts with various receptors and scaffolding proteins, thereby facilitating the clustering of neurotransmitter receptors and ensuring effective synaptic transmission. The structural integrity of PSD-95 is essential for function, as PSD-95 contains multiple protein-protein interaction domains that allow formation of complexes with other synaptic proteins, such as NMDA and AMPA receptors. Dysregulation of PSD-95 has been implicated in several neurological disorders, highlighting PSD-95′s importance in maintaining synaptic health and function. Anti-PSD-95 antibody (6G6) is an invaluable tool for researchers studying synaptic dynamics and the molecular mechanisms underlying neurodevelopmental and neurodegenerative diseases.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSD-95 Antibody (6G6) | sc-32291 | 200 µg/ml | $316.00 | |||
PSD-95 Antibody (6G6): m-IgG Fc BP-HRP Bundle | sc-536733 | 200 µg Ab; 10 µg BP | $354.00 | |||
PSD-95 Antibody (6G6): m-IgGκ BP-HRP Bundle | sc-533894 | 200 µg Ab; 40 µg BP | $354.00 |