Date published: 2025-10-17

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PSD-95 Antibody (6G6): sc-32291

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Datasheets
  • PSD-95 Antibody (6G6) is a mouse monoclonal IgG2a κ, cited in 11 publications, provided at 200 µg/ml
  • raised against purified recombinant PSD-95 of rat origin
  • recommended for detection of PSD-95 of mouse, rat and human origin by WB, IP and IF
  • See PSD-95 (7E3): sc-32290 for PSD-95 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PSD-95 Antibody (6G6) for WB applications. These reagents are now offered in bundles with PSD-95 Antibody (6G6) (see ordering information below).

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PSD-95 Antibody (6G6) is a mouse monoclonal IgG2a light chain antibody that detects PSD-95 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PSD-95, a member of the membrane-associated guanylate kinase (MAGUK) family, plays a crucial role in the organization of synaptic signaling complexes in neurons, which is vital for proper synaptic function and plasticity. PSD-95 is primarily located at the postsynaptic density of excitatory synapses, where PSD-95 interacts with various receptors and scaffolding proteins, thereby facilitating the clustering of neurotransmitter receptors and ensuring effective synaptic transmission. The structural integrity of PSD-95 is essential for function, as PSD-95 contains multiple protein-protein interaction domains that allow formation of complexes with other synaptic proteins, such as NMDA and AMPA receptors. Dysregulation of PSD-95 has been implicated in several neurological disorders, highlighting PSD-95′s importance in maintaining synaptic health and function. Anti-PSD-95 antibody (6G6) is an invaluable tool for researchers studying synaptic dynamics and the molecular mechanisms underlying neurodevelopmental and neurodegenerative diseases.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PSD-95 Antibody (6G6)

sc-32291
200 µg/ml
$316.00

PSD-95 Antibody (6G6): m-IgG Fc BP-HRP Bundle

sc-536733
200 µg Ab; 10 µg BP
$354.00

PSD-95 Antibody (6G6): m-IgGκ BP-HRP Bundle

sc-533894
200 µg Ab; 40 µg BP
$354.00

What is the recommended starting dilution for Western blot for sc-32291: PSD-95 (6G6) monoclonal antibody?

Asked by: Professor Griffin
The recommended starting dilution for Western blot is 1:100 with a dilution range of 1:100-1:1000. This information, along with other technical specifications, is available in the recommended protocol: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting
Answered by: Technical Support
Date published: 2017-03-22
  • y_2025, m_10, d_14, h_6CST
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Rated 5 out of 5 by from strong signalThe use of this antibody WB in 1:1000 shows strong signal and clear bands. This antibody played an important role in my experiment.
Date published: 2017-06-03
Rated 5 out of 5 by from Great Western Blot dataGreat Western Blot data of PSD-95 expression in HeLa whole cell lysates,recommend Hela cell for positive control.
Date published: 2017-02-12
Rated 5 out of 5 by from good resultOur laboratory has focused on the protein expression, we used this antibody to detect mouse kidney tissue, diluted 1:500, and obtained a specific strong band.
Date published: 2017-01-17
Rated 4 out of 5 by from Positive result in WB in mouse brain tissuePositive result in WB in mouse brain tissue extract. -SCBT QC
Date published: 2015-05-17
Rated 4 out of 5 by from IHC publishable data with rat hippocampal neuronsIHC publishable data with rat hippocampal neurons - SCBT Publication Review
Date published: 2014-02-27
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PSD-95 Antibody (6G6) is rated 4.6 out of 5 by 5.
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