Protein C Antibody (AMPC-9071): sc-73466

Protein C Antibody (AMPC-9071) is a rat monoclonal IgG antibody that detects Protein C in mouse samples through western blotting (WB). Protein C is a crucial vitamin K-dependent plasma protein synthesized in the liver, consisting of two polypeptide chains. Anti-Protein C antibody (AMPC-9071) recognizes a protein that acts as an important anticoagulant, which is activated by thrombin when bound to an endothelial surface receptor. Once activated, Protein C enzymatically cleaves the activated forms of coagulation factors V and VIII, thereby inhibiting blood coagulation and playing a vital role in maintaining hemostatic balance. The structure of Protein C is notably similar to that of the prothrombin group of blood coagulation factors, which underscores the evolutionary conservation of mechanisms regulating blood clotting. Normal concentrations of Protein C in human plasma range from approximately 1-3 ng/ml, with proenzyme levels around 3 µg/ml. Deficiencies in Protein C can lead to inherited thrombophilia, a rare genetic disorder that increases the risk of venous thrombosis and habitual abortion, highlighting the importance of this protein in both coagulation and overall vascular health. Protein C (AMPC-9071) antibody serves as an essential tool for researchers studying coagulation pathways and related disorders.

The preferred Protein C antibody is Protein C Antibody (C-10): sc-377175.