PROSER2 Antibody (G-11): sc-514063
- PROSER2 Antibody (G-11) is a mouse monoclonal IgG2a κ PROSER2 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 181-198 within an internal region of PROSER2 of human origin
- PROSER2 Antibody (G-11) is recommended for detection of PROSER2 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-PROSER2 Antibody (G-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PROSER2 Antibody (G-11) for WB applications. These reagents are now offered in bundles with PROSER2 Antibody (G-11) (see ordering information below).
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PROSER2 Antibody (G-11) is a mouse monoclonal IgG2a kappa light chain antibody that detects PROSER2 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PROSER2 (G-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. PROSER2 protein plays a crucial role in the regulation of neuronal differentiation and is involved in the development of the central nervous system, making PROSER2 significant for understanding neurodevelopmental disorders. PROSER2 expression is particularly important during embryonic development, where PROSER2 influences the fate of neural progenitor cells. Additionally, aberrations in PROSER2 expression have been linked to various neurological conditions, highlighting PROSER2 as a potential biomarker for disease states. PROSER2 localization within the cytoplasm and interactions with other signaling molecules underscore PROSER2′s importance in cellular communication and function. By utilizing anti-PROSER2 antibody (G-11), researchers can gain insights into the mechanisms underlying neuronal development and associated pathologies, facilitating advancements in therapeutic strategies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PROSER2 Antibody (G-11) References:
- Report of the third international workshop on human chromosome 10 mapping and sequencing 1999. | Deloukas, P., et al. 2000. Cytogenet Cell Genet. 90: 1-12. PMID: 11060438
- Chromosome 10. | Gilbert, F. 2001. Genet Test. 5: 69-82. PMID: 11336406
- Molecular cell biology of Charcot-Marie-Tooth disease. | Berger, P., et al. 2002. Neurogenetics. 4: 1-15. PMID: 12030326
- Cowden syndrome-affected patients with PTEN promoter mutations demonstrate abnormal protein translation. | Teresi, RE., et al. 2007. Am J Hum Genet. 81: 756-67. PMID: 17847000
- First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity. | Cho, MY., et al. 2008. Am J Surg Pathol. 32: 1258-64. PMID: 18594467
- PTEN: a new guardian of the genome. | Yin, Y. and Shen, WH. 2008. Oncogene. 27: 5443-53. PMID: 18794879
- Mutation update for the CSB/ERCC6 and CSA/ERCC8 genes involved in Cockayne syndrome. | Laugel, V., et al. 2010. Hum Mutat. 31: 113-26. PMID: 19894250
- Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2. | Jabs, EW., et al. 1994. Nat Genet. 8: 275-9. PMID: 7874170
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PROSER2 Antibody (G-11) | sc-514063 | 200 µg/ml | $316.00 | |||
PROSER2 Antibody (G-11): m-IgG Fc BP-HRP Bundle | sc-531019 | 200 µg Ab; 10 µg BP | $354.00 | |||
PROSER2 Antibody (G-11): m-IgGκ BP-HRP Bundle | sc-524593 | 200 µg Ab, 40 µg BP | $354.00 | |||
PROSER2 Antibody (G-11): m-IgG2a BP-HRP Bundle | sc-547664 | 200 µg Ab; 10 µg BP | $354.00 | |||
PROSER2 Antibody (G-11) AC | sc-514063 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PROSER2 Antibody (G-11) HRP | sc-514063 HRP | 200 µg/ml | $316.00 | |||
PROSER2 Antibody (G-11) FITC | sc-514063 FITC | 200 µg/ml | $330.00 | |||
PROSER2 Antibody (G-11) PE | sc-514063 PE | 200 µg/ml | $343.00 | |||
PROSER2 Antibody (G-11) Alexa Fluor® 488 | sc-514063 AF488 | 200 µg/ml | $357.00 | |||
PROSER2 Antibody (G-11) Alexa Fluor® 546 | sc-514063 AF546 | 200 µg/ml | $357.00 | |||
PROSER2 Antibody (G-11) Alexa Fluor® 594 | sc-514063 AF594 | 200 µg/ml | $357.00 | |||
PROSER2 Antibody (G-11) Alexa Fluor® 647 | sc-514063 AF647 | 200 µg/ml | $357.00 | |||
PROSER2 Antibody (G-11) Alexa Fluor® 680 | sc-514063 AF680 | 200 µg/ml | $357.00 | |||
PROSER2 Antibody (G-11) Alexa Fluor® 790 | sc-514063 AF790 | 200 µg/ml | $357.00 | |||
PROSER2 (G-11) Neutralizing Peptide | sc-514063 P | 100 µg/0.5 ml | $68.00 |