PRMT1 Antibody (G-6) is a mouse monoclonal IgG2a κ, cited in 2 publications, provided at 200 µg/ml
raised against amino acids 166-300 mapping within an internal region of PRMT1 of human origin
recommended for detection of PRMT1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
m-IgGκ BP-HRP is the preferred secondary detection reagent for PRMT1 Antibody (G-6) for WB applications. This reagent is now offered in a bundle with PRMT1 Antibody (G-6) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
A class of proteins termed type 1 protein arginine N-methyltransferase (PRMTs) enzymes contribute to post-translational modification of RNA-binding proteins, but differ in substrate specificities, oligomerization properties, and subcellular localization. PRMT1, the predominant form in mammalian cells, is located in the nucleus. At the carboxy terminus, Interleukin enhancer-binding factor 3 (ILF3) binds PRMT1, thereby regulating PRMT1 activity. Alternative mRNA splicing of the PRMT gene results in three isoforms of PRMT1 that differ in their amino terminus regions, all of which are enzymatically active. PRMT8, also known as HRMT1L3 or HRMT1L4 (heterogenous nuclear ribonucleioprotein methyltransferase-like protein 4), is a distinct member of the type 1 PRMT family with tissue-specific expression and plasma membrane localization. PRMT8 is specifically expressed in the brain where it functions as an arginine methyltransferase with a possible role in neuronal differentiation. It is most closely related to PRMT1 and may have arisen through a gene duplication. PRMT8 can heterodimerize with PRMT1 and has similar substrate preference.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.