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Prefoldin 3 Antibody (B-3) is a mouse monoclonal IgG1 antibody that detects prefoldin 3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Prefoldin 3, also known as VHL binding protein-1, plays a crucial role in cellular stress response by facilitating proper protein folding, particularly under conditions where misfolding can lead to cellular dysfunction. Prefoldin 3 is primarily located in the cytoplasm and forms complexes with the von Hippel-Lindau (VHL) tumor suppressor protein, which is essential for regulating hypoxia-inducible factors and maintaining cellular oxygen homeostasis. The interaction between prefoldin 3 and VHL is significant because this binding aids in VHL stabilization and influences hypoxia-inducible factor degradation, thereby impacting various cellular processes such as angiogenesis and metabolism. Anti-prefoldin 3 antibody (B-3) serves as an invaluable tool for researchers studying protein folding mechanisms and cellular stress response pathways.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
prefoldin 3 Antibody (B-3) | sc-390465 | 200 µg/ml | $322.00 | |||
prefoldin 3 Antibody (B-3): m-IgG Fc BP-HRP Bundle | sc-540804 | 200 µg Ab; 10 µg BP | $361.00 | |||
prefoldin 3 Antibody (B-3): m-IgG1 BP-HRP Bundle | sc-542379 | 200 µg Ab; 20 µg BP | $361.00 |