PPP1R12C Antibody (H-10): sc-398415
- PPP1R12C Antibody (H-10) is a mouse monoclonal IgG2a κ PPP1R12C antibody provided at 200 µg/ml
- raised against amino acids 271-420 mapping within an internal region of PPP1R12C of human origin
- PPP1R12C Antibody (H-10) is recommended for detection of PPP1R12C of human origin by WB, IP, IF and ELISA
- Anti-PPP1R12C Antibody (H-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PPP1R12C Antibody (H-10) for WB applications. These reagents are now offered in bundles with PPP1R12C Antibody (H-10) (see ordering information below).
PPP1R12C Antibody (H-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects PPP1R12C protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PPP1R12C (H-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PPP1R12C plays a crucial role in regulating myosin light chain phosphatase, which is essential for controlling smooth muscle contraction and cellular motility. This regulation is vital for numerous physiological processes, including vascular tone and blood pressure regulation, making PPP1R12C a significant player in cardiovascular health. Additionally, aberrations in PPP1R12C function have been implicated in various diseases, including cancer and cardiovascular disorders, highlighting its importance as a potential therapeutic target. With diverse applications and critical role in cellular functions, anti-PPP1R12C antibody (H-10) is an invaluable tool for researchers studying the intricate mechanisms of cell signaling and muscle contraction in human health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PPP1R12C Antibody (H-10) References:
- A fine physical map of the CACNA1A gene region on 19p13.1-p13.2 chromosome. | Trettel, F., et al. 2000. Gene. 241: 45-50. PMID: 10607897
- Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). | LaPoint, SF., et al. 2000. Adv Anat Pathol. 7: 307-21. PMID: 10976909
- Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters. | Moodie, SJ., et al. 2002. Eur J Immunogenet. 29: 287-91. PMID: 12121272
- Search for the second Peutz-Jeghers syndrome locus: exclusion of the STK13, PRKCG, KLK10, and PSCD2 genes on chromosome 19 and the STK11IP gene on chromosome 2. | Buchet-Poyau, K., et al. 2002. Cytogenet Genome Res. 97: 171-8. PMID: 12438709
- The DNA sequence and biology of human chromosome 19. | Grimwood, J., et al. 2004. Nature. 428: 529-35. PMID: 15057824
- Immunogenetics of killer cell immunoglobulin-like receptors. | Parham, P. 2005. Mol Immunol. 42: 459-62. PMID: 15607799
- BCL3 is induced by IL-6 via Stat3 binding to intronic enhancer HS4 and represses its own transcription. | Brocke-Heidrich, K., et al. 2006. Oncogene. 25: 7297-304. PMID: 16732314
- A novel CADASIL-causing mutation in a stroke patient. | Vikelis, M., et al. 2007. Swiss Med Wkly. 137: 323-5. PMID: 17629811
- Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors. | Zimmermann, W., et al. 1988. Cancer Res. 48: 2550-4. PMID: 3356015
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PPP1R12C Antibody (H-10) | sc-398415 | 200 µg/ml | $316.00 | |||
PPP1R12C Antibody (H-10): m-IgG Fc BP-HRP Bundle | sc-530786 | 200 µg Ab; 10 µg BP | $354.00 | |||
PPP1R12C Antibody (H-10): m-IgGκ BP-HRP Bundle | sc-524328 | 200 µg Ab, 40 µg BP | $354.00 | |||
PPP1R12C Antibody (H-10): m-IgG2a BP-HRP Bundle | sc-547588 | 200 µg Ab; 10 µg BP | $354.00 | |||
PPP1R12C Antibody (H-10) AC | sc-398415 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PPP1R12C Antibody (H-10) HRP | sc-398415 HRP | 200 µg/ml | $316.00 | |||
PPP1R12C Antibody (H-10) FITC | sc-398415 FITC | 200 µg/ml | $330.00 | |||
PPP1R12C Antibody (H-10) PE | sc-398415 PE | 200 µg/ml | $343.00 | |||
PPP1R12C Antibody (H-10) Alexa Fluor® 488 | sc-398415 AF488 | 200 µg/ml | $357.00 | |||
PPP1R12C Antibody (H-10) Alexa Fluor® 546 | sc-398415 AF546 | 200 µg/ml | $357.00 | |||
PPP1R12C Antibody (H-10) Alexa Fluor® 594 | sc-398415 AF594 | 200 µg/ml | $357.00 | |||
PPP1R12C Antibody (H-10) Alexa Fluor® 647 | sc-398415 AF647 | 200 µg/ml | $357.00 | |||
PPP1R12C Antibody (H-10) Alexa Fluor® 680 | sc-398415 AF680 | 200 µg/ml | $357.00 | |||
PPP1R12C Antibody (H-10) Alexa Fluor® 790 | sc-398415 AF790 | 200 µg/ml | $357.00 |