POPX2 Antibody (SJ-6): sc-100416
- POPX2 Antibody (SJ-6) is a mouse monoclonal IgG2a κ provided at 100 µg/ml
- raised against recombinant POPX2 of human origin
- recommended for detection of POPX2 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for POPX2 Antibody (SJ-6). This work is in progress.
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POPX2 Antibody (SJ-6) is a mouse monoclonal IgG2a antibody that detects POPX2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). POPX2, also known as partner of PIX 2, PPM1F, or CaMKPase, is a member of the PP2C family of serine/threonine phosphatases, which play a crucial role in regulating cellular stress response pathways. POPX2 is ubiquitously expressed, allowing participation in various cellular processes, including the modulation of calcium/calmodulin-dependent protein kinase II (CaMKII) activity, which is vital for synaptic plasticity and memory formation. POPX2′s ability to interact with and regulate CaMKII underscores its importance in neuronal signaling and potential implications in neurodegenerative diseases when dysregulated. Additionally, POPX2′s interaction with PIX proteins and role in negatively regulating αPAK activity highlight involvement in maintaining cytoskeletal integrity and cellular morphology. Overexpression of POPX2 has been linked to caspase-dependent apoptosis, further emphasizing significance in cell survival and death pathways. With diverse functional roles, POPX2 remains a critical protein for understanding cellular dynamics and underlying mechanisms of various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
POPX2 Antibody (SJ-6) | sc-100416 | 100 µg/ml | $333.00 |