POFUT2 Antibody (H-5): sc-373804
- POFUT2 Antibody (H-5) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 291-327 within an internal region of POFUT2 of human origin
- recommended for detection of POFUT2 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for POFUT2 Antibody (H-5) for WB applications. These reagents are now offered in bundles with POFUT2 Antibody (H-5) (see ordering information below).
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POFUT2 Antibody (H-5) is a mouse monoclonal IgG2b antibody that detects POFUT2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). POFUT2, also known as FUT13 or O-FucT-2, plays a critical role in transferring fucose to serine or threonine residues within properly folded thrombospondin repeats (TSRs) via an O-glycosidic linkage, which is essential for regulating cell surface carbohydrate profiles that facilitate biological recognition processes. POFUT2 localization in the endoplasmic reticulum is particularly important, as this cellular compartment is crucial for protein synthesis and folding, ensuring proteins achieve correct conformation before transport to functional destinations. POFUT2 exists in three isoforms (designated A, B, and C), each exhibiting distinct expression patterns, which may contribute to functional diversity of fucosylation in various biological contexts. POFUT2 may possess chaperone-like activity, aiding in quality control and proper protein folding, thereby influencing cellular processes such as signaling and adhesion.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
POFUT2 Antibody (H-5) | sc-373804 | 200 µg/ml | $322.00 | |||
POFUT2 Antibody (H-5): m-IgGκ BP-HRP Bundle | sc-535315 | 200 µg Ab; 40 µg BP | $361.00 | |||
POFUT2 Antibody (H-5): m-IgG2b BP-HRP Bundle | sc-549390 | 200 µg Ab; 10 µg BP | $361.00 | |||
POFUT2 (H-5) Neutralizing Peptide | sc-373804 P | 100 µg/0.5 ml | $69.00 |