PMPCA Antibody (F-4): sc-390718
- PMPCA Antibody (F-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 111-340 mapping within an internal region of PMPCA of human origin
- recommended for detection of PMPCA of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for PMPCA Antibody (F-4) for WB applications. These reagents are now offered in bundles with PMPCA Antibody (F-4) (see ordering information below).
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PMPCA Antibody (F-4) is a mouse monoclonal IgG1 antibody that detects PMPCA (peptidase (mitochondrial processing) alpha) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PMPCA is a 525 amino acid protein that plays a crucial role in mitochondrial function by cleaving transit peptides from mitochondrial protein precursors, which is essential for proper import and processing of proteins into mitochondria. This process is vital for maintaining mitochondrial integrity and function, as PMPCA ensures proteins are correctly localized and activated within the organelle, thereby supporting cellular energy production and metabolism. PMPCA exists as a heterodimer composed of alpha and beta subunits and is encoded by a gene located on human chromosome 9, a region associated with various genetic disorders, including hereditary hemorrhagic telangiectasia and familial dysautonomia. The significance of PMPCA in mitochondrial processing highlights anti-PMPCA antibody (F-4) as an invaluable tool for scientists studying mitochondrial diseases and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PMPCA Antibody (F-4) | sc-390718 | 200 µg/ml | $322.00 | |||
PMPCA Antibody (F-4): m-IgG Fc BP-HRP Bundle | sc-540842 | 200 µg Ab; 10 µg BP | $361.00 | |||
PMPCA Antibody (F-4): m-IgG1 BP-HRP Bundle | sc-542409 | 200 µg Ab; 20 µg BP | $361.00 |