PLEKHM3 Antibody (H-2): sc-393150
- PLEKHM3 Antibody (H-2) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-21 at the N-terminus of PLEKHM3 of human origin
- recommended for detection of PLEKHM3 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and avian
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PLEKHM3 Antibody (H-2) for WB applications. These reagents are now offered in bundles with PLEKHM3 Antibody (H-2) (see ordering information below).
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PLEKHM3 Antibody (H-2) is a mouse monoclonal IgG2a antibody that detects PLEKHM3 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PLEKHM3, also known as DAPR or PLEKHM1L, is a 761 amino acid phosphoprotein characterized by the presence of two pleckstrin homology (PH) domains and a phorbol-ester/DAG-type zinc finger, which are crucial for its role in cellular signaling and membrane trafficking. Anti-PLEKHM3 antibody (H-2) recognizes a protein involved in regulating intracellular transport processes, particularly in endosomal and lysosomal pathways, making PLEKHM3 essential for maintaining cellular homeostasis and responding to environmental stimuli. PLEKHM3 is conserved across various species, including chimpanzees, dogs, cows, mice, rats, chickens, and zebrafish, and exists in three alternatively spliced isoforms that facilitate metal ion binding, further underscoring its functional versatility. The gene encoding PLEKHM3 is located on human chromosome 2q33.3, a region that is significant not only for its genetic content—housing over 1,400 genes—but also for its evolutionary history, as this region formed from the fusion of two ancestral chromosomes, highlighting the complexity of human genetics. PLEKHM3 monoclonal antibody (H-2) serves as an invaluable tool for researchers studying the intricate mechanisms of cell biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PLEKHM3 Antibody (H-2) | sc-393150 | 200 µg/ml | $316.00 | |||
PLEKHM3 Antibody (H-2): m-IgG Fc BP-HRP Bundle | sc-538154 | 200 µg Ab; 10 µg BP | $354.00 | |||
PLEKHM3 Antibody (H-2): m-IgGκ BP-HRP Bundle | sc-535714 | 200 µg Ab; 40 µg BP | $354.00 | |||
PLEKHM3 Antibody (H-2): m-IgG2a BP-HRP Bundle | sc-548220 | 200 µg Ab; 10 µg BP | $354.00 | |||
PLEKHM3 (H-2) Neutralizing Peptide | sc-393150 P | 100 µg/0.5 ml | $68.00 |