PLEKHA5 Antibody (E-2): sc-390311
- PLEKHA5 Antibody (E-2) is a mouse monoclonal IgG2b κ PLEKHA5 antibody, cited in 4 publications, provided at 200 µg/ml
- raised against amino acids 216-470 mapping within an internal region of PLEKHA5 of human origin
- PLEKHA5 Antibody (E-2) is recommended for detection of PLEKHA5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-PLEKHA5 Antibody (E-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PLEKHA5 Antibody (E-2) for WB and IHC(P) applications. These reagents are now offered in bundles with PLEKHA5 Antibody (E-2) (see ordering information below).
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PLEKHA5 Antibody (E-2) is a mouse monoclonal IgG2b kappa light chain antibody that detects PLEKHA5 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-PLEKHA5 antibody (E-2) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PLEKHA5, also known as pleckstrin homology domain containing, family A member 5, KIAA1686, or PEPP2, is a 1,116 amino acid protein characterized by one pleckstrin homology (PH) domain and two WW domains, which are critical for protein-protein interactions. PLEKHA5 is predominantly expressed in kidney and heart tissues, highlighting a potential role in cardiovascular and renal functions. PLEKHA5 participates in cellular signaling pathways that regulate cell growth and differentiation, making PLEKHA5 essential for maintaining normal physiological processes. The gene encoding PLEKHA5 is located on human chromosome 12, a region associated with various skeletal deformities and crucial transcription factors for morphogenesis, underscoring PLEKHA5′s importance in developmental biology and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PLEKHA5 Antibody (E-2) References:
- Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. | Dowler, S., et al. 2000. Biochem J. 351: 19-31. PMID: 11001876
- Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. | Nagase, T., et al. 2000. DNA Res. 7: 347-55. PMID: 11214970
- The genomic context of natural killer receptor extended gene families. | Trowsdale, J., et al. 2001. Immunol Rev. 181: 20-38. PMID: 11513141
- Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia. | Montpetit, A., et al. 2004. Leukemia. 18: 1499-504. PMID: 15284860
- Genotype/phenotype analysis in a patient with pure and complete trisomy 12p. | Zumkeller, W., et al. 2004. Am J Med Genet A. 129A: 261-4. PMID: 15326625
- Comparative genomics of natural killer cell receptor gene clusters. | Kelley, J., et al. 2005. PLoS Genet. 1: 129-39. PMID: 16132082
- The natural history of trisomy 12p. | Segel, R., et al. 2006. Am J Med Genet A. 140: 695-703. PMID: 16502429
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PLEKHA5 Antibody (E-2) | sc-390311 | 200 µg/ml | $316.00 | |||
PLEKHA5 Antibody (E-2): m-IgGκ BP-HRP Bundle | sc-523486 | 200 µg Ab, 40 µg BP | $354.00 | |||
PLEKHA5 Antibody (E-2): m-IgG2b BP-HRP Bundle | sc-549120 | 200 µg Ab; 10 µg BP | $354.00 | |||
PLEKHA5 Antibody (E-2) AC | sc-390311 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PLEKHA5 Antibody (E-2) HRP | sc-390311 HRP | 200 µg/ml | $316.00 | |||
PLEKHA5 Antibody (E-2) FITC | sc-390311 FITC | 200 µg/ml | $330.00 | |||
PLEKHA5 Antibody (E-2) PE | sc-390311 PE | 200 µg/ml | $343.00 | |||
PLEKHA5 Antibody (E-2) Alexa Fluor® 488 | sc-390311 AF488 | 200 µg/ml | $357.00 | |||
PLEKHA5 Antibody (E-2) Alexa Fluor® 546 | sc-390311 AF546 | 200 µg/ml | $357.00 | |||
PLEKHA5 Antibody (E-2) Alexa Fluor® 594 | sc-390311 AF594 | 200 µg/ml | $357.00 | |||
PLEKHA5 Antibody (E-2) Alexa Fluor® 647 | sc-390311 AF647 | 200 µg/ml | $357.00 | |||
PLEKHA5 Antibody (E-2) Alexa Fluor® 680 | sc-390311 AF680 | 200 µg/ml | $357.00 | |||
PLEKHA5 Antibody (E-2) Alexa Fluor® 790 | sc-390311 AF790 | 200 µg/ml | $357.00 |