PKC beta 2 Antibody (F-7): sc-13149
- PKC beta 2 Antibody (F-7) is a mouse monoclonal IgG1 κ, cited in 45 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 657-673 at the C-terminus of PKC βII of human origin
- Anti-PKC beta 2 Antibody (F-7) is recommended for detection of cPKC βII of mouse, rat and human origin by WB, IP, IF, IHC(P), FCM and ELISA; also reactive with additional species, including and bovine and porcine
- Anti-PKC beta 2 Antibody (F-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PKC beta 2 Antibody (F-7) for WB and IHC(P) applications. These reagents are now offered in bundles with PKC beta 2 Antibody (F-7) (see ordering information below).
PKC βII Antibody (F-7) is a mouse monoclonal IgG1 kappa light chain antibody engineered to target the PKC βII isoform of protein kinase C with exceptional precision. PKC βII monoclonal antibody (F-7) binds to a defined epitope located between amino acids 657-673 at the C-terminus of human PKC βII, ensuring accurate detection and minimal cross-reactivity. PKC βII is a crucial member of the protein kinase C family, which plays a pivotal role in various cellular signaling pathways that regulate essential processes such as cell growth, differentiation, apoptosis, gene expression, hormone secretion, and membrane function. PKC βII (F-7) antibody exhibits broad species reactivity, effectively recognizing PKC βII in mouse, rat, and human samples, as well as in additional species like bovine and porcine, across a range of applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin embedded sections (IHC/P), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Available in both non-conjugated form and various conjugated versions such as agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, PKC βII (F-7) monoclonal antibody provides versatile options for researchers.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PKC beta 2 Antibody (F-7) References:
- A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle. | Osada, S., et al. 1992. Mol Cell Biol. 12: 3930-8. PMID: 1508194
- Structural and functional diversities of a family of signal transducing protein kinases, protein kinase C family; two distinct classes of PKC, conventional cPKC and novel nPKC. | Ohno, S., et al. 1991. Adv Enzyme Regul. 31: 287-303. PMID: 1877391
- Expression and characterization of protein kinase C-delta. | Olivier, AR. and Parker, PJ. 1991. Eur J Biochem. 200: 805-10. PMID: 1915352
- Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. | Takai, Y., et al. 1979. J Biol Chem. 254: 3692-5. PMID: 438153
- Turnover of inositol phospholipids and signal transduction. | Nishizuka, Y. 1984. Science. 225: 1365-70. PMID: 6147898
- The role of protein kinase C in cell surface signal transduction and tumour promotion. | Nishizuka, Y. Nature. 308: 693-8. PMID: 6232463
- Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters. | Kikkawa, U., et al. 1983. J Biol Chem. 258: 11442-5. PMID: 6311812
- Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters. | Castagna, M., et al. 1982. J Biol Chem. 257: 7847-51. PMID: 7085651
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PKC beta 2 Antibody (F-7) | sc-13149 | 200 µg/ml | $316.00 | |||
PKC beta 2 Antibody (F-7): m-IgG Fc BP-HRP Bundle | sc-528271 | 200 µg Ab; 10 µg BP | $354.00 | |||
PKC beta 2 Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-520610 | 200 µg Ab, 40 µg BP | $354.00 | |||
PKC beta 2 Antibody (F-7) AC | sc-13149 AC | 500 µg/ml, 25% agarose | $416.00 | |||
PKC beta 2 Antibody (F-7) HRP | sc-13149 HRP | 200 µg/ml | $316.00 | |||
PKC beta 2 Antibody (F-7) FITC | sc-13149 FITC | 200 µg/ml | $330.00 | |||
PKC beta 2 Antibody (F-7) PE | sc-13149 PE | 200 µg/ml | $343.00 | |||
PKC beta 2 Antibody (F-7) Alexa Fluor® 488 | sc-13149 AF488 | 200 µg/ml | $357.00 | |||
PKC beta 2 Antibody (F-7) Alexa Fluor® 546 | sc-13149 AF546 | 200 µg/ml | $357.00 | |||
PKC beta 2 Antibody (F-7) Alexa Fluor® 594 | sc-13149 AF594 | 200 µg/ml | $357.00 | |||
PKC beta 2 Antibody (F-7) Alexa Fluor® 647 | sc-13149 AF647 | 200 µg/ml | $357.00 | |||
PKC beta 2 Antibody (F-7) Alexa Fluor® 680 | sc-13149 AF680 | 200 µg/ml | $357.00 | |||
PKC beta 2 Antibody (F-7) Alexa Fluor® 790 | sc-13149 AF790 | 200 µg/ml | $357.00 | |||
PKC beta 2 (F-7) Neutralizing Peptide | sc-13149 P | 100 µg/0.5 ml | $68.00 |