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PHF6 Antibody (C-6) is a mouse monoclonal IgG1 antibody that detects PHF6 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PHF6, also known as PHD finger protein 6 or BORJ, is a 365 amino acid protein that plays a crucial role in transcriptional regulation and is predominantly localized in the nucleus. The presence of two PHD-type zinc fingers in PHF6′s structure allows direct interaction with specific DNA sequences, thereby influencing gene expression. This function is vital for normal cellular processes, as dysregulation of transcription can lead to various diseases, including cancer. Notably, mutations in the gene encoding PHF6 are linked to Boerjeson-Forssman-Lehmann syndrome (BFLS), an X-linked recessive disorder characterized by a range of symptoms including mental retardation, epilepsy, and obesity. Anti-PHF6 antibody (C-6) is essential for researchers studying the implications of PHF6 in both normal physiology and disease states, providing a reliable tool for investigating PHF6′s role in transcriptional regulation and cellular function.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PHF6 Antibody (C-6) | sc-514644 | 200 µg/ml | $322.00 | |||
PHF6 Antibody (C-6): m-IgG Fc BP-HRP Bundle | sc-538680 | 200 µg Ab; 10 µg BP | $361.00 | |||
PHF6 Antibody (C-6): m-IgGκ BP-HRP Bundle | sc-536335 | 200 µg Ab; 40 µg BP | $361.00 | |||
PHF6 Antibody (C-6): m-IgG1 BP-HRP Bundle | sc-545826 | 200 µg Ab; 20 µg BP | $361.00 | |||
PHF6 (C-6) Neutralizing Peptide | sc-514644 P | 100 µg/0.5 ml | $69.00 |