Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Phosducin is a phototransducing protein that may participate in the feedback regulation of visual phototransduction or in the integration of photoreceptor metabolism. The human phosducin gene maps to chromosome 1q25-q31.1 and encodes a 246 amino acid protein, also designated Phd. Phd is primarily expressed in the retina and the pineal gland, while lower levels are present in tissues such as liver, spleen, striated muscle and the brain. Retinal Phd is found exclusively in the outer and inner segments of photoreceptor cells, including the synaptic and nuclear layers. Phd modulates the phototransduction cascade through high affinity binding and sequestration of G beta/gamma subunits of heterotrimeric G proteins. Neutralization of G beta/gamma by phosducin inhibits G protein-mediated signaling, since G alpha is unable to reassemble with G beta/gamma and provide a functional G protein trimer (G alpha/beta/gamma). In addition, phosducin can effectively slow down the mechanism of internalization of G protein-coupled opioid receptors.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.