PHACTR1 Antibody (E-2): sc-514800
- PHACTR1 Antibody (E-2) is a mouse monoclonal IgG2a λ PHACTR1 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 53-67 near the N-terminus of PHACTR1 of human origin
- PHACTR1 Antibody (E-2) is recommended for detection of PHACTR1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-PHACTR1 Antibody (E-2) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGλ BP-HRP are the preferred secondary detection reagents for PHACTR1 Antibody (E-2) for WB applications. These reagents are now offered in bundles with PHACTR1 Antibody (E-2) (see ordering information below).
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PHACTR1 Antibody (E-2) is a mouse monoclonal IgG2a antibody that detects PHACTR1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PHACTR1 (E-2) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. PHACTR1, also known as phosphatase and actin regulator 1, plays a crucial role in regulating actin cytoskeleton and is involved in cellular processes such as cell migration and adhesion. PHACTR1′s proper function is vital for maintaining cellular architecture and facilitating communication between cells, which is essential for tissue integrity and response to external stimuli. PHACTR1 is a 580 amino acid cytoplasmic protein that exists in two alternatively spliced isoforms and contains RPEL repeats, indicating involvement in actin dynamics. PHACTR1 gene is located on human chromosome 6, a region associated with various diseases, including early onset intestinal cancer and porphyria cutanea tarda, highlighting PHACTR1′s importance in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
PHACTR1 Antibody (E-2) References:
- Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins. | Allen, PB., et al. 2004. Proc Natl Acad Sci U S A. 101: 7187-92. PMID: 15107502
- Assignment of the PHACTR1 gene to bovine chromosome 23q24 by fluorescence in situ hybridization and radiation hybrid mapping. | Drögemüller, C., et al. 2005. Cytogenet Genome Res. 109: 533. PMID: 15906473
- The HLA-A1-B8 haplotype hitchhiking with the hemochromatosis mutation: does it affect the phenotype? | Olsson, KS., et al. 2007. Eur J Haematol. 79: 429-34. PMID: 17924859
- Recurrent deletions at 6q in early age of onset non-HNPCC- and non-FAP-associated intestinal carcinomas. Evidence for a novel cancer susceptibility locus at 6q14-q22. | Bläker, H., et al. 2008. Genes Chromosomes Cancer. 47: 159-64. PMID: 18008368
- A sclerodermiform porphyria cutanea tarda. | Amezyane, T., et al. 2010. Intern Med. 49: 205-6. PMID: 20075595
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PHACTR1 Antibody (E-2) | sc-514800 | 200 µg/ml | $322.00 | |||
PHACTR1 Antibody (E-2): m-IgGλ BP-HRP Bundle | sc-524846 | 200 µg Ab, 40 µg BP | $361.00 | |||
PHACTR1 Antibody (E-2): m-IgG2a BP-HRP Bundle | sc-546241 | 200 µg Ab; 10 µg BP | $361.00 | |||
PHACTR1 Antibody (E-2) AC | sc-514800 AC | 500 µg/ml, 25% agarose | $424.00 | |||
PHACTR1 Antibody (E-2) HRP | sc-514800 HRP | 200 µg/ml | $322.00 | |||
PHACTR1 Antibody (E-2) FITC | sc-514800 FITC | 200 µg/ml | $336.00 | |||
PHACTR1 Antibody (E-2) PE | sc-514800 PE | 200 µg/ml | $349.00 | |||
PHACTR1 Antibody (E-2) Alexa Fluor® 488 | sc-514800 AF488 | 200 µg/ml | $364.00 | |||
PHACTR1 Antibody (E-2) Alexa Fluor® 546 | sc-514800 AF546 | 200 µg/ml | $364.00 | |||
PHACTR1 Antibody (E-2) Alexa Fluor® 594 | sc-514800 AF594 | 200 µg/ml | $364.00 | |||
PHACTR1 Antibody (E-2) Alexa Fluor® 647 | sc-514800 AF647 | 200 µg/ml | $364.00 | |||
PHACTR1 Antibody (E-2) Alexa Fluor® 680 | sc-514800 AF680 | 200 µg/ml | $364.00 | |||
PHACTR1 Antibody (E-2) Alexa Fluor® 790 | sc-514800 AF790 | 200 µg/ml | $364.00 | |||
PHACTR1 (E-2) Neutralizing Peptide | sc-514800 P | 100 µg/0.5 ml | $69.00 |