Peroxin 5 Antibody (B-9): sc-365629
- Peroxin 5 Antibody (B-9) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 127-154 within an internal region of Peroxin 5 of human origin
- recommended for detection of Peroxin 5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and porcine
- m-IgG2b BP-HRP is the preferred secondary detection reagent for Peroxin 5 Antibody (B-9) for WB and IHC(P) applications. This reagent is now offered in a bundle with Peroxin 5 Antibody (B-9) (see ordering information below).
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Peroxin 5 Antibody (B-9) is a mouse monoclonal IgG2b antibody that detects Peroxin 5 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Peroxin 5, also known as the peroxisome targeting signal 1 (PTS1) receptor, plays a crucial role in the import of proteins into peroxisomes, which are essential organelles involved in lipid metabolism and the detoxification of reactive oxygen species. Peroxin 5 is primarily located in the cytosol, where PTS1-containing proteins bind and facilitate transport to peroxisomes, ensuring proper organelle function and cellular homeostasis. The significance of Peroxin 5′s location is underscored by involvement in peroxisome biogenesis disorders; mutations in the Pex5 gene can lead to severe conditions such as Zellweger syndrome, characterized by profound neurological impairment and early mortality. Anti-Peroxin 5 antibody (B-9) enables researchers to gain insights into the mechanisms of peroxisome function and the pathological consequences of dysfunction, making this tool invaluable for studies in cell biology and disease research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Peroxin 5 Antibody (B-9) | sc-365629 | 200 µg/ml | $322.00 | |||
Peroxin 5 Antibody (B-9): m-IgG2b BP-HRP Bundle | sc-548559 | 200 µg Ab; 10 µg BP | $361.00 | |||
Peroxin 5 (B-9) Neutralizing Peptide | sc-365629 P | 100 µg/0.5 ml | $69.00 |