CD31/PECAM-1 Antibody (JC70): sc-53411
- CD31/PECAM-1 Antibody (JC70) is a mouse monoclonal IgG1 κ, cited in 32 publications, provided at 200 µg/ml
- raised against spleen of human origin
- CD31/PECAM-1 Antibody (JC70) is recommended for detection of PECAM-1 of human origin by WB, IP, IF, IHC(P) and FCM
- Anti-CD31/PECAM-1 Antibody (JC70) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CD31/PECAM-1 Antibody (JC70) for WB and IHC(P) applications. These reagents are now offered in bundles with CD31/PECAM-1 Antibody (JC70) (see ordering information below).
QUICK LINKS
PECAM-1 Antibody (JC70) is a mouse monoclonal IgG1 kappa light chain antibody that detects human PECAM-1 through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-PECAM-1 antibody (JC70) is available in non-conjugated form and conjugated to agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® dyes. PECAM-1, also known as CD31, is a crucial glycoprotein expressed on monocytes, neutrophils, platelets, and select T cells, playing a vital role in cell-cell adhesion and signaling during immune responses and inflammation. PECAM-1 is predominantly located at endothelial cell intercellular junctions, facilitating leukocyte transmigration from bloodstream to tissues - a process essential for immune surveillance and injury response. PECAM-1 also contributes to angiogenesis and vascular integrity maintenance, serving as a significant marker in cardiovascular disease and tumor biology research. PECAM-1′s interactions with adhesion molecules, including integrins, highlight its significance in cellular communication and immune response regulation.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD31/PECAM-1 Antibody (JC70) | sc-53411 | 200 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (JC70): m-IgG Fc BP-HRP Bundle | sc-526807 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD31/PECAM-1 Antibody (JC70): m-IgG1 BP-HRP Bundle | sc-532180 | 200 µg Ab; 20 µg BP | $354.00 | |||
CD31/PECAM-1 Antibody (JC70) AC | sc-53411 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CD31/PECAM-1 Antibody (JC70) HRP | sc-53411 HRP | 200 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (JC70) FITC | sc-53411 FITC | 200 µg/ml | $330.00 | |||
CD31/PECAM-1 Antibody (JC70) PE | sc-53411 PE | 200 µg/ml | $343.00 | |||
CD31/PECAM-1 Antibody (JC70) Alexa Fluor® 488 | sc-53411 AF488 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (JC70) Alexa Fluor® 546 | sc-53411 AF546 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (JC70) Alexa Fluor® 594 | sc-53411 AF594 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (JC70) Alexa Fluor® 647 | sc-53411 AF647 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (JC70) Alexa Fluor® 680 | sc-53411 AF680 | 200 µg/ml | $357.00 | |||
CD31/PECAM-1 Antibody (JC70) Alexa Fluor® 790 | sc-53411 AF790 | 200 µg/ml | $357.00 |