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PECAM-1 Antibody (3H1217) is a mouse monoclonal IgG1 antibody that detects PECAM-1 in mouse and rat samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). PECAM-1, also known as CD31, is a crucial glycoprotein primarily located on the surfaces of endothelial cells, platelets, and certain immune cells, playing a vital role in mediating cell-cell adhesion and signaling during inflammatory responses and angiogenesis. PECAM-1′s presence on endothelial cells facilitates the transmigration of leukocytes from the bloodstream into tissues, a process essential for immune surveillance and response to injury. Additionally, PECAM-1 functions in maintaining vascular barrier integrity, which is critical for preventing excessive leakage of fluids and proteins into surrounding tissues. PECAM-1′s significance in both normal physiological processes and pathological conditions, such as cancer metastasis and inflammatory diseases, makes anti-PECAM-1 antibody (3H1217) valuable for research and diagnostic applications, enabling scientists to explore PECAM-1′s role in various biological contexts.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD31/PECAM-1 Antibody (3H1217) | sc-71873 | 200 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (3H1217) FITC | sc-71873 FITC | 200 µg/ml | $330.00 | |||
CD31/PECAM-1 Antibody (3H1217) PE | sc-71873 PE | 200 µg/ml | $343.00 |