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PECAM-1 Antibody (0.N.100) is a mouse monoclonal IgG1 antibody that detects PECAM-1 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). PECAM-1, also known as CD31, is a crucial glycoprotein that plays a significant role in the regulation of leukocyte migration and angiogenesis, making PECAM-1 essential for maintaining vascular integrity and facilitating immune responses. PECAM-1 is predominantly located at the intercellular junctions of endothelial cells, where PECAM-1 mediates cell-cell adhesion and communication, thereby influencing the permeability of blood vessels and the transmigration of immune cells during inflammatory responses. Proper functioning of PECAM-1 is vital for normal physiological processes, as PECAM-1 dysregulation has been implicated in various pathological conditions, including chronic inflammation and cancer metastasis. By utilizing anti-PECAM-1 antibody (0.N.100), researchers can gain valuable insights into the mechanisms of vascular biology and immune cell interactions, furthering our understanding of diseases associated with endothelial dysfunction.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD31/PECAM-1 Antibody (0.N.100) | sc-71872 | 200 µg/ml | $316.00 | |||
CD31/PECAM-1 Antibody (0.N.100): m-IgGκ BP-HRP Bundle | sc-521098 | 200 µg Ab, 40 µg BP | $354.00 | |||
CD31/PECAM-1 Antibody (0.N.100) FITC | sc-71872 FITC | 200 µg/ml | $330.00 | |||
CD31/PECAM-1 Antibody (0.N.100) PE | sc-71872 PE | 200 µg/ml | $343.00 |