PDI Antibody (F-11): sc-166474
- PDI Antibody (F-11) is a mouse monoclonal IgG3 κ, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 151-170 within an internal region of PDI of human origin
- recommended for detection of precursor and mature PDI of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See PDI (C-2): sc-74551 for PDI antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgGκ BP-HRP is the preferred secondary detection reagent for PDI Antibody (F-11) for WB and IHC(P) applications. This reagent is now offered in a bundle with PDI Antibody (F-11) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
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PDI Antibody (F-11) is a mouse monoclonal IgG3 antibody that detects protein disulfide isomerase (PDI) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-PDI antibody (F-11) recognizes PDI, a crucial protein that plays a significant role in the folding and maturation of newly synthesized proteins within the endoplasmic reticulum (ER). PDI (F-11) antibody targets a protein essential for maintaining cellular homeostasis, as PDI catalyzes thiol-disulfide exchange reactions, which are vital for proper formation of disulfide bonds in proteins. PDI functions as a molecular chaperone to aid in correct protein folding and prevent aggregation of misfolded proteins, contributing to cellular stress responses. PDI engages in critical interactions with other proteins, such as immunoglobulin heavy chain binding protein (BiP), enhancing protein processing and quality control within the ER. PDI localization in the ER enables immediate assistance in protein folding during synthesis, ensuring proteins reach functional conformations efficiently. With diverse functions and interactions, PDI serves as a key player in cellular physiology, making PDI (F-11) monoclonal antibody an invaluable tool for researchers studying protein folding and related cellular processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PDI Antibody (F-11) | sc-166474 | 200 µg/ml | $322.00 | |||
PDI Antibody (F-11): m-IgGκ BP-HRP Bundle | sc-521622 | 200 µg Ab, 40 µg BP | $361.00 | |||
PDI (F-11) Neutralizing Peptide | sc-166474 P | 100 µg/0.5 ml | $69.00 |