Pax genes contain paired domains that share strong homology to genes in Drosophila which are involved in programming early development. The product of the PAX3 gene is a DNA-binding protein expressed during early neurogenesis. Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.
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Informations pour la commande
Nom du produit | Ref. Catalogue | COND. | Prix HT | QTÉ | Favoris | |
Anticorps Pax-3 (A-5) | sc-376215 | 200 µg/ml | $316.00 | |||
Pax-3 (A-5): m-IgG Fc BP-HRP Kit | sc-537980 | 200 µg Ab; 10 µg BP | $354.00 | |||
Pax-3 (A-5): m-IgGκ BP-HRP Kit | sc-535478 | 200 µg Ab; 40 µg BP | $354.00 | |||
Pax-3 (A-5): m-IgG1 BP-HRP Kit | sc-545474 | 200 µg Ab; 20 µg BP | $354.00 | |||
Pax-3 (A-5) peptide neutralisant | sc-376215 P | 100 µg/0.5 ml | $68.00 | |||
Anticorps Pax-3 (A-5) X | sc-376215 X | 200 µg/0.1 ml | $316.00 |