pan-Cytokeratin Antibody (AE13): sc-57012

pan-Cytokeratin Antibody (AE13) is a mouse monoclonal IgG1 kappa light chain antibody that detects pan-Cytokeratin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. anti-pan-Cytokeratin antibody (AE13) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cytokeratins, the target of pan-Cytokeratin monoclonal antibody (AE13), are a diverse group of intermediate filament proteins that are crucial for maintaining the structural integrity of epithelial cells. These proteins are expressed in pairs within both keratinized and non-keratinized epithelial tissues, playing a vital role in cellular differentiation and tissue specialization. Cytokeratins serve as valuable biomarkers for tissue differentiation, particularly relevant in malignant tumors. For example, cytokeratins 10 and 13 are prominently expressed in certain squamous cell carcinomas, while cytokeratin 18 is commonly found in adenocarcinomas and basal cell carcinomas, making pan-Cytokeratin (AE13) antibody an essential tool for researchers studying epithelial cell biology and cancer pathology.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-pan-Cytokeratin Antibody (AE13) has 14 citations in a variety of scientific publications.

Primary antibodies like Anti-pan-Cytokeratin Antibody (AE13) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

pan-Cytokeratin Antibody (AE13) Specifications

Alternate Product Name: Cytokeratin

Product Clone Name: AE13

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids:

Epitope Target: pan-Cytokeratin

Epitope Species: human

Product Reactivity/Detection: the family of hair cortex keratins

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P)

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 14 citations in various scientific publications

Available Conjugates/Forms for pan-Cytokeratin Antibody (AE13): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred pan-Cytokeratin antibody is pan-Cytokeratin Antibody (C11): sc-8018.