pan CEA Antibody (H-7): sc-398551
- pan CEA Antibody (H-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 111-162 within an internal region of CEACAM5 of human origin
- recommended for detection of CEACAM1, CEACAM3, CEACAM5 and CEACAM6 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for pan CEA Antibody (H-7) for WB applications. These reagents are now offered in bundles with pan CEA Antibody (H-7) (see ordering information below).
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SEE ALSO...
pan CEA Antibody (H-7) is a mouse monoclonal IgG1 antibody that detects carcinoembryonic antigen (CEA) in human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CEA antibody (H-7) is particularly valuable in clinical diagnostics as CEA serves as a critical tumor marker, primarily associated with various carcinomas, including colorectal cancer. CEA (H-7) monoclonal antibody recognizes proteins predominantly located on the cell surface, where CEA plays a significant role in cell adhesion and signaling, which are essential for maintaining tissue architecture and facilitating communication between cells. This localization is crucial because alterations in CEA expression can influence tumor progression and metastasis, making CEA a key focus in cancer research and therapeutic monitoring. Additionally, human CEACAM proteins, including CEA, are encoded by genes clustered on chromosome 19, highlighting their evolutionary significance and potential as biomarkers in oncology.
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pan CEA Antibody (H-7) References:
- Immunohistological investigations of carcinoembryonic antigen (CEA) in urothelial carcinomas. | Feil, G., et al. 1999. Anticancer Res. 19: 2591-7. PMID: 10470200
- Membranous expression of carcinoembryonic antigen (CEA) in the normal cervical squamous mucosa. | Sanders, DS., et al. 1992. J Pathol. 167: 77-82. PMID: 1625062
- Carcinoembryonic antigen (CEA) plasma level determination in the management of gastric cancer patients. | Dittrich, C., et al. 1985. Cancer Detect Prev. 8: 181-7. PMID: 4064038
- Carcinoembryonic antigen (CEA) plasma levels in untreated cancer patients and patients with metastatic disease. | Concannon, JP., et al. 1973. Radiology. 108: 191-3. PMID: 4709032
- Circulating immune complexes (CIC), carcinoembryonic antigen (CEA) and CIC containing CEA as markers for colorectal cancer. | Chester, KA. and Begent, RH. 1984. Clin Exp Immunol. 58: 685-93. PMID: 6509799
- Carcinoembryonic antigen (CEA) in the cancer family syndrome. | Guirgis, HA., et al. 1978. Cancer. 42: 1574-8. PMID: 709527
- Identification of carcinoembryonic antigen (CEA) in bile of patients with malignant biliary tract disease. | Konomi, K., et al. 1982. Jpn J Surg. 12: 184-90. PMID: 7131963
- Comparison of RIA and IRMA methods for measurement of carcinoembryonic antigen (CEA). | Valdes, R. and Stein, KE. 1982. Clin Biochem. 15: 241-7. PMID: 7151270
- Carcinoembryonic antigen (CEA) in patients with breast cancer. | Borthwick, NM., et al. 1977. Eur J Cancer (1965). 13: 171-6. PMID: 852488
- Neoplasms with sweat gland differentiation express various glycoproteins of the carcinoembryonic antigen (CEA) family. | Metze, D., et al. 1996. J Cutan Pathol. 23: 1-11. PMID: 8720980
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan CEA Antibody (H-7) | sc-398551 | 200 µg/ml | $322.00 | |||
pan CEA Antibody (H-7): m-IgG Fc BP-HRP Bundle | sc-538469 | 200 µg Ab; 10 µg BP | $361.00 | |||
pan CEA Antibody (H-7): m-IgGκ BP-HRP Bundle | sc-536091 | 200 µg Ab; 40 µg BP | $361.00 | |||
pan CEA Antibody (H-7): m-IgG1 BP-HRP Bundle | sc-545717 | 200 µg Ab; 20 µg BP | $361.00 | |||
pan CEA (H-7) Neutralizing Peptide | sc-398551 P | 100 µg/0.5 ml | $69.00 |