pan CEA Antibody (E-4): sc-48374
- pan CEA Antibody (E-4) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 35-334 of CEA (carcinoembryonic antigen) of human origin
- recommended for detection of a broad range of CEA (CD66 isoforms) family members and CEA related molecules of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for pan CEA Antibody (E-4) for WB and IHC(P) applications. These reagents are now offered in bundles with pan CEA Antibody (E-4) (see ordering information below).
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SEE ALSO...
pan CEA Antibody (E-4) is a mouse monoclonal IgG1 antibody that detects carcinoembryonic antigen (CEA) in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-CEA antibody (E-4) is particularly significant due to CEA′s crucial role in cell adhesion and signaling, which are vital processes in both normal physiological functions and pathological conditions such as cancer. CEA, a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family, is primarily expressed in epithelial tissues and is often upregulated in various carcinomas, making CEA a valuable tumor marker for monitoring disease progression and response to therapy. CEA′s structure, characterized by a single N domain and multiple immunoglobulin-like domains, facilitates interactions with other proteins and cells, influencing processes such as angiogenesis and immune response modulation. Understanding CEA′s structural attributes is essential for developing targeted therapies and improving diagnostic accuracy in oncology.
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pan CEA Antibody (E-4) References:
- Carcinoembryonic antigen (CEA), smoking, and cancer in a longitudinal population study. | Cullen, KJ., et al. 1976. Aust N Z J Med. 6: 279-83. PMID: 1070982
- The role of half-life of carcinoembryonic antigen (CEA) in prognosis prediction of colorectal cancer patients with preoperatively elevated CEA. | Yuan, SQ., et al. 2008. Ai Zheng. 27: 612-7. PMID: 18570735
- Elevated preoperative carcinoembryonic antigen (CEA) and Ki67 is predictor of decreased survival in IIA stage colon cancer. | Peng, Y., et al. 2013. World J Surg. 37: 208-13. PMID: 23052808
- Carcinoembryonic antigen (CEA) level, CEA ratio, and treatment outcome of rectal cancer patients receiving pre-operative chemoradiation and surgery. | Yang, KL., et al. 2013. Radiat Oncol. 8: 43. PMID: 23452434
- A carcinoembryonic antigen (CEA) binding protein from ascites influences CEA uptake by macrophages. | Toth, CA., et al. 1990. Biochem Biophys Res Commun. 171: 633-40. PMID: 2403353
- Prognostic impact of carcinoembryonic antigen (CEA) on patients with metastatic pancreatic cancer: A retrospective cohort study. | Imaoka, H., et al. 2016. Pancreatology. 16: 859-64. PMID: 27256641
- Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence. | Oikawa, S., et al. 1987. Biochem Biophys Res Commun. 142: 511-8. PMID: 3814146
- The immunogenicity of carcinoembryonic antigen (CEA) in athymic nude mice. | Lewis, JC. 1983. Exp Pathol. 24: 43-50. PMID: 6685055
- Localization and concentration of carcinoembryonic antigen (CEA) in gastrointestinal tumors: correlation with CEA levels in plasma. | Wagener, C., et al. 1981. J Natl Cancer Inst. 67: 539-47. PMID: 6944526
- Carcinoembryonic antigen (CEA) and CEA-related substances in the bile of patients with biliary diseases. | Uchino, R., et al. 1994. Am J Surg. 167: 306-8. PMID: 8160902
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan CEA Antibody (E-4) | sc-48374 | 200 µg/ml | $322.00 | |||
pan CEA Antibody (E-4): m-IgG Fc BP-HRP Bundle | sc-536819 | 200 µg Ab; 10 µg BP | $361.00 | |||
pan CEA Antibody (E-4): m-IgGκ BP-HRP Bundle | sc-533986 | 200 µg Ab; 40 µg BP | $361.00 | |||
pan CEA Antibody (E-4): m-IgG1 BP-HRP Bundle | sc-544839 | 200 µg Ab; 20 µg BP | $361.00 |