Date published: 2026-5-6
Visit Santa Cruz Animal Health

1-800-457-3801

SCBT Portrait Logo
Seach Input
Contact Us
Sign In Account
Quick Order
Cart (0)
pan CEA Antibody (C-4) - Western Blotting - Image 305650
pan CEA Antibody (C-4): sc-398504. Western blot analysis of pan CEA expression in LS1034 (A) and T84 (B) whole cell lysates.
pan CEA Antibody (C-4) - Western Blotting - Image 305650
pan CEA Antibody (C-4): sc-398504. Western blot analysis of pan CEA expression in LS1034 (A) and T84 (B) whole cell lysates.
pan CEA Antibody (C-4) - Western Blotting - Image 360192
pan CEA Antibody (C-4): sc-398504. Western blot analysis of pan CEA expression in MCF7 (A) and Raji (B) whole cell lysates.
pan CEA Antibody (C-4): sc-398504. Western blot analysis of pan CEA expression in LS1034 (A) and T84 (B) whole cell lysates.

pan CEA Antibody (C-4): sc-398504

5.0(1)
Write a reviewAsk a question

Datasheets
  • pan CEA Antibody (C-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 122-143 within an internal region of CEACAM5 of human origin
  • recommended for detection of a broad range of CEACAM family members of human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for pan CEA Antibody (C-4) for WB applications. These reagents are now offered in bundles with pan CEA Antibody (C-4) (see ordering information below).
    Gene Editing Promo Banner

    QUICK LINKS

    Support Products
    Description
    Gene Info
    Datasheets and Protocols
    Research Information

    SEE ALSO...

    Pan CEA Antibody (C-4) is a mouse monoclonal IgG1 antibody that detects carcinoembryonic antigen (CEA) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-CEA antibody (C-4) is particularly valuable in clinical diagnostics as CEA serves as a critical tumor marker, primarily associated with various carcinomas, including colorectal cancer. CEA (C-4) monoclonal antibody recognizes proteins predominantly located on the cell surface, where CEA plays a significant role in cell adhesion and signaling, which are essential for maintaining tissue architecture and facilitating communication between cells. This localization is crucial because alterations in CEA expression can influence tumor progression and metastasis, making CEA a key focus in cancer research and therapeutic monitoring. Additionally, human CEACAM proteins, including CEA, are encoded by genes clustered on chromosome 19, and CEA expression levels can provide insights into disease states, thereby aiding in the assessment of treatment efficacy and disease prognosis.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    pan CEA Antibody (C-4) References:

    1. Bypassing immunization: optimized design of 'designer T cells' against carcinoembryonic antigen (CEA)-expressing tumors, and lack of suppression by soluble CEA.  |  Nolan, KF., et al. 1999. Clin Cancer Res. 5: 3928-41. PMID: 10632322
    2. Prognostic value of carcinoembryonic antigen (CEA) in tumor tissue of patients with colorectal cancer.  |  Nakagoe, T., et al. 2001. Anticancer Res. 21: 3031-6. PMID: 11712806
    3. Inhibition of endogenous carcinoembryonic antigen (CEA) increases the apoptotic rate of colon cancer cells and inhibits metastatic tumor growth.  |  Wirth, T., et al. 2002. Clin Exp Metastasis. 19: 155-60. PMID: 11964079
    4. Identification of an interferon-gamma-inducible carcinoembryonic antigen (CEA) CD8(+) T-cell epitope, which mediates tumor killing in CEA transgenic mice.  |  Schmitz, J., et al. 2002. Cancer Res. 62: 5058-64. PMID: 12208761
    5. A monoclonal antibody against neem leaf glycoprotein recognizes carcinoembryonic antigen (CEA) and restricts CEA expressing tumor growth.  |  Das, A., et al. 2014. J Immunother. 37: 394-406. PMID: 25198527
    6. The carcinoembryonic antigen (CEA) contains multiple immunoglobulin-like domains.  |  Oikawa, S., et al. 1987. Biochem Biophys Res Commun. 144: 634-42. PMID: 3579935
    7. Carcinoembryonic antigen (CEA) assay. A laboratory adjunct in the diagnosis and management of cancer.  |  Hansen, HJ., et al. 1974. Hum Pathol. 5: 139-47. PMID: 4811605
    8. Binding reactivity of monoclonal anti-carcinoembryonic antigen (CEA) antibodies with cell membrane-bound CEA and with free CEA in solution.  |  Murakami, M., et al. 1996. Immunol Invest. 25: 23-35. PMID: 8675232
    9. The carcinoembryonic antigen (CEA) modulates effector-target cell interaction by binding to activated lymphocytes.  |  Kammerer, R. and von Kleist, S. 1996. Int J Cancer. 68: 457-63. PMID: 8945616
    10. Carcinoembryonic antigen (CEA) in ovarian cancer: factors influencing its incidence and changes which occur in response to cytotoxic drugs.  |  Khoo, SK. and MacKay, EV. 1976. Br J Obstet Gynaecol. 83: 753-9. PMID: 990213

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    pan CEA Antibody (C-4)

    sc-398504
    200 µg/ml
    		$322.00

    pan CEA Antibody (C-4): m-IgG Fc BP-HRP Bundle

    sc-538459
    200 µg Ab; 10 µg BP
    		$361.00

    pan CEA Antibody (C-4): m-IgGκ BP-HRP Bundle

    sc-536080
    200 µg Ab; 40 µg BP
    		$361.00

    pan CEA Antibody (C-4): m-IgG1 BP-HRP Bundle

    sc-545712
    200 µg Ab; 20 µg BP
    		$361.00

    pan CEA (C-4) Neutralizing Peptide

    sc-398504 P
    100 µg/0.5 ml
    		$69.00

    What application is the blocking peptide sc-398504 P appropriate for?

    Asked by: DefinitelyNotMatt
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_5, d_5, h_11CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.43
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_en_US, sid_398504, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 99ms
    • QUESTIONS, PRODUCT
    Rated 5 out of 5 by from Very good Western blot data of pan CEA expressionVery good Western blot data of pan CEA expression in LS1034 and T84 whole cell lysates. -SCBT QC
    Date published: 2014-01-04
    • y_2026, m_5, d_5, h_11
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_en_US, sid_398504, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 31ms
    • REVIEWS, PRODUCT
    pan CEA Antibody (C-4) is rated 5.0 out of 5 by 1.
    • y_2026, m_5, d_5, h_11
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.43
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_1
    • loc_en_US, sid_398504, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 95ms
    • REVIEWS, PRODUCT
    1-800-457-3801
    Visit Santa Cruz Animal Health|Visit San Juan Ranch
    Santa Cruz Animal Health is a leading provider of animal health care products. ©2026 Santa Cruz Biotechnology Inc. All Rights Reserved.
    Toll-Free: 1-800-457-3801 - Terms & Conditions | Privacy Policy | Legal
    “Santa Cruz Animal Health”, “San Juan Ranch”, the San Juan Ranch logo, “UltraCruz”, “Supplement of Champions”, are registered trademarks of Santa Cruz Biotechnology, Inc. All other trademarks are the property of their respective owners.