p41-ARCb Antibody (C-4): sc-137202
- p41-ARCb Antibody (C-4) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 291-344 mapping near the C-terminus of p41-ARCb of human origin
- recommended for detection of p41-ARCb of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP is the preferred secondary detection reagent for p41-ARCb Antibody (C-4) for WB applications. This reagent is now offered in a bundle with p41-ARCb Antibody (C-4) (see ordering information below).
p41-ARCb Antibody (C-4) is a mouse monoclonal IgG2b antibody that detects p41-ARCb in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p41-ARCb, also known as ARPC1B or ARC41, is a 372 amino acid subunit of the Arp2/3 complex, which plays a crucial role in regulating actin polymerization and forming branched actin networks. p41-ARCb is primarily localized in the cytoplasm and cytoskeleton, where p41-ARCb maintains the structural integrity of the Arp2/3 complex. Unlike other subunits of the complex, p41-ARCb doesn′t directly participate in actin polymerization but instead supports complex assembly and maintenance, which drives cellular processes like motility, shape, and division. Multiple isoforms of p41-ARCb exist due to post-translational modifications, showcasing functional diversity that adapts to various cellular contexts and developmental stages. Through interactions with other Arp2/3 complex proteins, p41-ARCb orchestrates dynamic changes in the actin cytoskeleton, making p41-ARCb a valuable research target in cell biology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p41-ARCb Antibody (C-4) | sc-137202 | 200 µg/ml | $322.00 | |||
p41-ARCb Antibody (C-4): m-IgG2b BP-HRP Bundle | sc-548507 | 200 µg Ab; 10 µg BP | $361.00 |