p35 Antibody (4G11): sc-293184
- p35 Antibody (4G11) is a mouse monoclonal IgG2a κ p35 antibody, cited in 6 publications, provided at 100 µg/ml
- raised against amino acids 208-307 representating a partial fragment of p35 human origin
- recommended for detection of p35 of mouse, rat and human origin by WB, IP, IF and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p35 Antibody (4G11). This work is in progress.
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p35 Antibody (4G11) is a mouse monoclonal IgG2a kappa light chain antibody that detects p35 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-p35 antibody (4G11) is available as the non-conjugated format. p35 protein, also known as CDK5R1, plays a crucial role in regulating cyclin-dependent kinase 5 (Cdk5), which is essential for proper neuronal function and development. Cdk5 is particularly important in the brain, where Cdk5 regulates processes such as neuronal migration, synaptic plasticity, and cell cycle control. p35 interaction with Cdk5 is vital, as p35 activates Cdk5′s kinase activity, allowing Cdk5 to phosphorylate various substrates involved in these critical neuronal processes. p35 is predominantly expressed in the brain, while a truncated form known as p25 can be found in other tissues, which may have implications for neurodegenerative diseases when p25 accumulates. p35 (4G11) antibody′s specificity and functionality make p35 (4G11) antibody an invaluable tool for researchers studying the intricate roles of Cdk5 and regulatory mechanisms in both normal and pathological states.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p35 Antibody (4G11) | sc-293184 | 100 µg/ml | $322.00 |