CDKN2A/p16 Antibody (50.1): sc-9968
- CDKN2A/p16 Antibody (50.1) is a mouse monoclonal IgG1, cited in 43 publications, provided at 200 µg/ml
- raised against full length p16 INK4A of human origin
- recommended for detection of p16 INK4A of human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CDKN2A/p16 Antibody (50.1) for WB and IHC(P) applications. These reagents are now offered in bundles with CDKN2A/p16 Antibody (50.1) (see ordering information below).
p16 INK4A Antibody (50.1) is a mouse monoclonal IgG1 antibody that detects p16 INK4A in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry (IHC), and enzyme-linked immunosorbent assay (ELISA). p16 INK4A plays a crucial role as a negative regulator of the cell cycle, specifically inhibiting cyclin-dependent kinase 4 (Cdk4) activity, which is essential for controlling cell proliferation during the G1 phase. By binding to Cdk4, p16 INK4A prevents the formation of the active Cdk4/cyclin D complex, thereby halting the progression of the cell cycle and maintaining cellular integrity. This regulatory function is particularly important in the context of tumor suppression, as the gene encoding p16 INK4A is frequently subject to homozygous deletions and point mutations in various human tumor cell lines, highlighting its significance in cancer biology. p16 INK4A monoclonal antibody (50.1) effectively detects this target protein, making p16 INK4A (50.1) antibody a valuable tool for researchers studying cell cycle regulation and its implications in cancer development.
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CDKN2A/p16 Antibody (50.1) | sc-9968 | 200 µg/ml | $322.00 | |||
CDKN2A/p16INK4a Antibody (50.1): m-IgG Fc BP-HRP Bundle | sc-536565 | 200 µg Ab; 10 µg BP | $361.00 | |||
CDKN2A/p16INK4a Antibody (50.1): m-IgGκ BP-HRP Bundle | sc-533716 | 200 µg Ab; 40 µg BP | $361.00 | |||
CDKN2A/p16INK4a Antibody (50.1): m-IgG1 BP-HRP Bundle | sc-544679 | 200 µg Ab; 20 µg BP | $361.00 |