p14ARF Antibody (3F16): sc-71797
- p14ARF Antibody (3F16) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against recombinant p14 ARF of human origin
- recommended for detection of p14 ARF of human origin by WB, IP and IF
- See p14ARF (ARF 4C6/4): sc-53392 for p14ARF antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for p14ARF Antibody (3F16) for WB applications. These reagents are now offered in bundles with p14ARF Antibody (3F16) (see ordering information below).
p14 ARF Antibody (3F16) is a mouse monoclonal IgG1 antibody that detects p14 ARF in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). p14 ARF plays a crucial role in regulating the cell cycle by acting as a tumor suppressor, particularly through interaction with the MDM2 protein. anti-p14 ARF antibody (3F16) stabilizes p53 by inhibiting MDM2, which is responsible for targeting p53 for degradation. By preventing p53 degradation, p14 ARF promotes cell cycle arrest, allowing for DNA repair or apoptosis in response to cellular stress or damage. p14 ARF′s ability to modulate MDM2 and p21 levels further underscores its importance in maintaining genomic integrity and preventing tumorigenesis. p14 ARF monoclonal antibody (3F16) serves as an essential tool for researchers studying cell cycle regulation mechanisms and pathways involved in cancer development.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p14ARF Antibody (3F16) | sc-71797 | 200 µg/ml | $322.00 | |||
p14ARF Antibody (3F16): m-IgG Fc BP-HRP Bundle | sc-539407 | 200 µg Ab; 10 µg BP | $361.00 | |||
p14ARF Antibody (3F16): m-IgG1 BP-HRP Bundle | sc-541472 | 200 µg Ab; 20 µg BP | $361.00 |