p-Tau Antibody (6A192): sc-71794

p-Tau Antibody (6A192) is a mouse monoclonal IgG1 antibody that detects p-Tau in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. p-Tau, a phosphorylated form of the microtubule-associated protein tau, plays a critical role in the regulation of microtubule stability and neuronal function. p-Tau (6A192) antibody targets proteins primarily located in the cytoplasm and is essential for maintaining the structural integrity of neurons, as p-Tau helps to stabilize microtubules, which are vital for intracellular transport and overall cell shape. Proper functioning of p-Tau is crucial for neuronal health, as dysregulation can lead to neurodegenerative diseases such as Alzheimer′s disease, where hyperphosphorylation of tau leads to the formation of neurofibrillary tangles, a hallmark of the disease. p-Tau undergoes various post-translational modifications, which can influence interactions with other proteins and overall function within the cell. Anti-p-Tau antibody (6A192) is an invaluable tool for researchers studying tau pathology and its implications in neurodegenerative disorders, providing insights into the mechanisms underlying these diseases and potential therapeutic targets.

The preferred Tau antibody is Tau Antibody (Tau 46): sc-32274.