p-PKC alpha Antibody (pT638.35): sc-517540

p-PKC α Antibody (pT638.35) is a mouse monoclonal IgG1 kappa light chain antibody that detects the Thr 638 phosphorylated PKC α protein of mouse, rat, and human origin by western blotting (WB) and immunoprecipitation (IP). anti-PKC α antibody (pT638.35) is available in a non-conjugated form, allowing for versatile applications in various experimental setups. The protein kinase C (PKC) family, to which PKC α belongs, is integral to numerous cellular processes, including cell growth, differentiation, and apoptosis, making PKC α a critical target for understanding signaling pathways in health and disease. PKC α is primarily located in the cytoplasm and translocates to the membrane upon activation, which is essential for mediating signal transduction. This translocation allows PKC α to interact with various substrates and participate in downstream signaling cascades that regulate cellular responses to external stimuli. PKC α undergoes several post-translational modifications, including phosphorylation, which can modulate activity and function. Phosphorylation at Thr 638 enhances PKC α′s enzymatic activity, thereby influencing cellular signaling. Understanding PKC α dynamics, including activation and interaction with other proteins, is vital for elucidating contributions to various physiological and pathological processes.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-p-PKC alpha Antibody (pT638.35) has 3 citations in a variety of scientific publications.

Primary antibodies like Anti-p-PKC alpha Antibody (pT638.35) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

p-PKC alpha Antibody (pT638.35) Specifications

Alternate Product Name: PKC alpha

Product Clone Name: pT638.35

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: Thr 638

Epitope Target: PKC α

Epitope Species: human

Product Reactivity/Detection: Thr 638 phosphorylated PKC α

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 3 citations in various scientific publications

Available Conjugates/Forms for p-PKC alpha Antibody (pT638.35): N/A

The preferred PKC antibody is PKC Antibody (A-9): sc-17804.