p-FAK Antibody (A-12): sc-374668
- p-FAK Antibody (A-12) is a mouse monoclonal IgG1 κ, cited in 14 publications, provided at 200 µg/ml
- p-FAK Antibody (A-12) is recommended for detection of Ser 722 phosphorylated FAK of mouse, rat, human and origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine and avian
- Anti-p-FAK Antibody (A-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for p-FAK Antibody (A-12) for WB and IHC(P) applications. These reagents are now offered in bundles with p-FAK Antibody (A-12) (see ordering information below).
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SEE ALSO...
p-FAK Antibody (A-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects Ser 722 phosphorylated FAK of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). p-FAK (A-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Focal adhesion kinase (FAK) plays a critical role in cellular signaling pathways, particularly in integrin-mediated adhesion to the extracellular matrix (ECM). FAK is primarily located at focal adhesions, specialized structures forming at the interface between cells and ECM. This localization enables FAK to interact with integrins and other signaling molecules, facilitating signal transmission that regulates cell migration, proliferation, and survival. Dynamic phosphorylation of FAK at specific tyrosine residues, such as Tyr 397 and Tyr 407, is essential for function, as phosphorylation modulates focal adhesion assembly and disassembly in response to extracellular cues. Using anti-FAK antibody (A-12), researchers can gain insights into regulatory mechanisms of cell behavior and FAK signaling implications in various physiological and pathological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-FAK Antibody (A-12) | sc-374668 | 200 µg/ml | $322.00 | |||
p-FAK Antibody (A-12): m-IgG Fc BP-HRP Bundle | sc-527498 | 200 µg Ab; 10 µg BP | $361.00 | |||
p-FAK Antibody (A-12): m-IgG1 BP-HRP Bundle | sc-532871 | 200 µg Ab; 20 µg BP | $361.00 | |||
p-FAK Antibody (A-12) AC | sc-374668 AC | 500 µg/ml, 25% agarose | $424.00 | |||
p-FAK Antibody (A-12) HRP | sc-374668 HRP | 200 µg/ml | $322.00 | |||
p-FAK Antibody (A-12) FITC | sc-374668 FITC | 200 µg/ml | $336.00 | |||
p-FAK Antibody (A-12) PE | sc-374668 PE | 200 µg/ml | $349.00 | |||
p-FAK Antibody (A-12) Alexa Fluor® 488 | sc-374668 AF488 | 200 µg/ml | $364.00 | |||
p-FAK Antibody (A-12) Alexa Fluor® 546 | sc-374668 AF546 | 200 µg/ml | $364.00 | |||
p-FAK Antibody (A-12) Alexa Fluor® 594 | sc-374668 AF594 | 200 µg/ml | $364.00 | |||
p-FAK Antibody (A-12) Alexa Fluor® 647 | sc-374668 AF647 | 200 µg/ml | $364.00 | |||
p-FAK Antibody (A-12) Alexa Fluor® 680 | sc-374668 AF680 | 200 µg/ml | $364.00 | |||
p-FAK Antibody (A-12) Alexa Fluor® 790 | sc-374668 AF790 | 200 µg/ml | $364.00 | |||
p-FAK (A-12) Neutralizing Peptide | sc-374668 P | 100 µg/0.5 ml | $69.00 |