OX2R Antibody (OX110): sc-53103
- OX2R Antibody (OX110) is a rat monoclonal IgG1 provided at 200 µg/ml
- raised against fusion protein mCD200RCD4d3+4 of mouse origin
- recommended for detection of OX2R of mouse origin by FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for OX2R Antibody (OX110). This work is in progress.
QUICK LINKS
OX2R Antibody (OX110) is a rat monoclonal IgG1 antibody that detects OX2R in mouse samples through flow cytometry (FCM). OX2R, also known as the OX2 receptor, is a critical membrane protein predominantly expressed in lymphoid and neuronal tissues, playing a significant role in immune regulation and neuronal signaling. The structure of OX2R features a cytoplasmic domain rich in NPXY motifs, which are essential for interactions with phosphotyrosine-binding (PTB) domains, facilitating downstream signaling pathways. These interactions modulate immune responses, particularly in limiting macrophage-induced inflammatory damage in tissues, thereby maintaining homeostasis. OX2R′s extensive N-linked glycosylation, accounting for up to 70% of molecular weight, influences stability and function, highlighting the importance of post-translational modifications in immune response regulation. Anti-OX2R antibody (OX110) serves as an invaluable tool for researchers studying immune modulation and neuronal communication in mouse models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
OX2R Antibody (OX110) | sc-53103 | 200 µg/ml | $322.00 | |||
OX2R Antibody (OX110) FITC | sc-53103 FITC | 200 µg/ml | $336.00 | |||
OX2R Antibody (OX110) PE | sc-53103 PE | 200 µg/ml | $349.00 |