Oviductin Antibody (H-8): sc-377267

Oviductin Antibody (H-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects Oviductin protein of mouse, rat, human, and hamster origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Oviductin antibody (H-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Oviductin, also known as Mucin 9, is a member of the mucin family, which comprises highly glycosylated proteins characterized by a basic structure of variable number of tandem repeats (VNTRs). The unique structure of Oviductin, with extensive glycosylation, plays a crucial role in binding to the zona pellucida of oocytes, which is essential for successful fertilization and early embryonic development. Oviductin is predominantly localized in secretory granules within the oviduct and reaches peak expression during ovulation, highlighting significance in reproductive processes. The ability of Oviductin to interact with specific proteins during fertilization makes Oviductin monoclonal antibody (H-8) a valuable tool for researchers studying fertility and embryonic development.

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Oviductin Antibody (H-8) References:

1. Oviductin (Muc9) is expressed in rabbit endocervix.  |  Hendrix, E., et al. 2001. Endocrinology. 142: 2151. PMID: 11316784
2. Regulation of human oviductin mRNA expression in vivo.  |  Briton-Jones, C., et al. 2001. Fertil Steril. 75: 942-6. PMID: 11334906
3. Oviductin, the oviductal protease that mediates gamete interaction by affecting the vitelline coat in Bufo japonicus: its molecular cloning and analyses of expression and posttranslational activation.  |  Hiyoshi, M., et al. 2002. Dev Biol. 243: 176-84. PMID: 11846486
4. Human oviductin mRNA expression is not maintained in oviduct mucosal cell culture.  |  Briton-Jones, C., et al. 2002. Fertil Steril. 77: 576-80. PMID: 11872215
5. Variable expression of oviductin mRNA at different stages of human reproductive cycle.  |  Lok, IH., et al. 2002. J Assist Reprod Genet. 19: 569-76. PMID: 12503889
6. Estradiol regulation of oviductin/oviduct-specific glycoprotein messenger ribonucleic acid expression in human oviduct mucosal cells in vitro.  |  Briton-Jones, C., et al. 2004. Fertil Steril. 81 Suppl 1: 749-56. PMID: 15019805
7. Expression of human oviductin in an immortalized human oviductal cell line.  |  Ling, L., et al. 2005. Fertil Steril. 84 Suppl 2: 1095-103. PMID: 16209999
8. The secretions of oviduct epithelial cells increase the equine in vitro fertilization rate: are osteopontin, atrial natriuretic peptide A and oviductin involved?  |  Mugnier, S., et al. 2009. Reprod Biol Endocrinol. 7: 129. PMID: 19925651
9. New paralogues and revised time line in the expansion of the vertebrate GH18 family.  |  Hussain, M. and Wilson, JB. 2013. J Mol Evol. 76: 240-60. PMID: 23558346
10. Human oviductal fluid (hOF) proteins. IV. Evidence for hOF proteins binding to human sperm.  |  Lippes, J. and Wagh, PV. 1989. Fertil Steril. 51: 89-94. PMID: 2642815
11. Human oviductal fluid proteins. III. Identification and partial purification.  |  Wagh, PV. and Lippes, J. 1989. Fertil Steril. 51: 81-8. PMID: 2910720
12. Complementary deoxyribonucleic acid cloning and molecular characterization of an estrogen-dependent human oviductal glycoprotein.  |  Arias, EB., et al. 1994. Biol Reprod. 51: 685-94. PMID: 7819450

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Oviductin Antibody (H-8) has 7 citations in a variety of scientific publications.

Primary antibodies like Anti-Oviductin Antibody (H-8) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Oviductin Antibody (H-8) Specifications

Alternate Product Name: Oviductin

Product Clone Name: H-8

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 632-721

Epitope Target: Oviductin (also designated Mucin 9)

Epitope Species: mouse

Product Reactivity/Detection: Oviductin

Species Reactivity/Detection: mouse, rat, human, hamster

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 7 citations in various scientific publications

Available Conjugates/Forms for Oviductin Antibody (H-8): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin