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The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs). The number of repeats is highly polymorphic and varies among different alleles. The mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. Mucin 9 (Muc9), often referred to as oviduct-specific glycoprotein (Oviductin) or estrogen-dependent oviduct protein, is an oviduct-specific protein. It binds to oocyte zona pellucida in vivo and is involved in the fertilization process and early embryonic development. Oviductin localizes to secretory granules and the protein is detected in OE-E6/E7 cell lines. During the human reproductive cycle, Oviductin expression is highest at the time of ovulation.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Oviductin, or OVGP1is known to be specifically expressed by the secretory cells of the oviductal epithelium and not expressed in normal ovarian tissue or ovarian oocytes. What ovarian tissue have you used for detect oviductin expression?
Asked by: SallyZh
Thank you for your question. At the time this testing was performed, Source said that >75% of OVGP1 expression happened in ovary. A current review on HPA shows no expression in ovary. We will have our lab review this IHC(P) data. In the meantime, please consider this alternative, Oviductin Antibody (H-8): sc-377267, which has more recent data in formalin fixed, paraffin-embedded human fallopian tube.
Answered by: Technical Support
Date published: 2019-07-12
What application is the blocking peptide sc-376300 P appropriate for?
Asked by: Professor Griffin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here:
Rated 5 out of
goodProtein is a highly glycosylated family of secreted proteins with a basic structure consisting of a variable number of tandem repeats that can be found in the literature, usually called tubal-specific glycoproteins or estrogen-dependent tubal proteins, which are tubal-specific proteins.
Date published: 2017-02-08
Rated 5 out of
detect the expression of OVNOviductin (Ovn) plays crucial role during fertilization and early embryonic development. We knock down the corresponding gene to research its function. We found this antibody can detect the decrease expression of OVN in animal.
Date published: 2016-12-18
Rated 5 out of
Produced exceptional immunoperoxidase cytoplasmicProduced exceptional immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human ovary tissue. -SCBT QC
Date published: 2015-05-20
Rated 5 out of
Nice Western Blot data of Oviductin expressionNice Western Blot data of Oviductin expression in Hep G2 whole cell lysate. -SCBT QC
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