OSM Antibody (G-7): sc-373734

OSM Antibody (G-7) is a mouse monoclonal IgG2b antibody that detects Oncostatin M (OSM) in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-OSM antibody (G-7) plays a crucial role in understanding the function of OSM, a glycoprotein that regulates cell growth and differentiation, particularly in hematopoietic cells. OSM (G-7) antibody enables research into a protein known for inhibiting proliferation of various human tumor cell lines while sparing normal human fibroblasts, highlighting OSM′s potential as a therapeutic target in cancer treatment. High-affinity binding sites for OSM on both normal and tumor cells underscore OSM′s significance in cellular signaling pathways. OSM expression is notably elevated in activated monocytic and lymphocytic cell lines, as well as in normal adherent macrophages, indicating OSM′s involvement in immune responses. OSM′s amino acid sequence shows homology with other important cytokines such as leukemia inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6, all integral to growth and differentiation of various cell types. OSM monoclonal antibody (G-7) enables researchers to explore OSM mechanisms and interactions within the cellular environment, paving the way for advancements in therapeutic strategies.

The preferred OSM antibody is OSM Antibody (A-9): sc-374039.