Orc2 Antibody (SB46): sc-56738
- Orc2 Antibody (SB46) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against full length recombinant ORC2 of S. cerevisiae origin
- recommended for detection of ORC2 of Saccharomyces cerevisiae origin by WB, IP and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Orc2 Antibody (SB46) for WB applications. These reagents are now offered in bundles with Orc2 Antibody (SB46) (see ordering information below).
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Orc2 Antibody (SB46) is a mouse monoclonal IgG1 antibody that detects Orc2 in Saccharomyces cerevisiae through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Orc2 (SB46) antibody recognizes a crucial component of the origin of replication complex (ORC), which is essential for the initiation of DNA replication. Orc2 plays a vital role in binding to autonomously replicating sequences (ARS), thereby facilitating the assembly of the minichromosome maintenance (MCM) proteins that are necessary for the regulation of DNA replication. The interaction of Orc2 with other proteins, such as Cdc6, ensures that DNA replication occurs only once per cell cycle, preventing genomic instability. Additionally, Orc2′s association with transcription factors like Abf1 highlights its dual role in both DNA replication and gene regulation, making Orc2 a key player in maintaining cellular integrity and function. Anti-Orc2 antibody (SB46) serves as an invaluable tool for researchers studying the mechanisms of DNA replication and the intricate regulatory networks that govern cell cycle progression in yeast.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Orc2 Antibody (SB46) | sc-56738 | 200 µg/ml | $322.00 | |||
Orc2 Antibody (SB46): m-IgG Fc BP-HRP Bundle | sc-539040 | 200 µg Ab; 10 µg BP | $361.00 | |||
Orc2 Antibody (SB46): m-IgG1 BP-HRP Bundle | sc-541223 | 200 µg Ab; 20 µg BP | $361.00 |