Orc2 Antibody (C-5): sc-398410
- Orc2 Antibody (C-5) is a mouse monoclonal IgG2a κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 611-622 near the C-terminus of Orc2 of Saccharomyces cerevisiae origin
- Orc2 Antibody (C-5) is recommended for detection of Orc2 of y origin by WB, IP, IF and ELISA
- Anti-Orc2 Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2a BP-HRP are the preferred secondary detection reagents for Orc2 Antibody (C-5) for WB applications. These reagents are now offered in bundles with Orc2 Antibody (C-5) (see ordering information below).
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Orc2 Antibody (C-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects Orc2 of yeast origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Orc2 (C-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Orc2, along with Orc1, is one of the six essential subunits of the yeast origin of replication complex (ORC), which is crucial for initiating DNA replication by binding to autonomously replicating sequences (ARS). The proper functioning of Orc2 is vital as Orc2 not only facilitates the assembly of the ORC-ARS complex but also interacts with other key proteins such as Cdc6, which ensures that DNA replication occurs only once per cell cycle. Additionally, Orc2′s interaction with minichromosome maintenance (MCM) proteins is critical for the regulation of DNA replication, as these proteins bind to chromatin and activate the replication process. Understanding the role of Orc2 in these interactions is important for elucidating the mechanisms of DNA replication and its regulation, which has significant implications in cell biology and cancer research.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Orc2 Antibody (C-5) | sc-398410 | 200 µg/ml | $322.00 | |||
Orc2 Antibody (C-5): m-IgG Fc BP-HRP Bundle | sc-526310 | 200 µg Ab; 10 µg BP | $361.00 | |||
Orc2 Antibody (C-5): m-IgG2a BP-HRP Bundle | sc-546577 | 200 µg Ab; 10 µg BP | $361.00 | |||
Orc2 Antibody (C-5) AC | sc-398410 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Orc2 Antibody (C-5) HRP | sc-398410 HRP | 200 µg/ml | $322.00 | |||
Orc2 Antibody (C-5) FITC | sc-398410 FITC | 200 µg/ml | $336.00 | |||
Orc2 Antibody (C-5) PE | sc-398410 PE | 200 µg/ml | $349.00 | |||
Orc2 Antibody (C-5) Alexa Fluor® 488 | sc-398410 AF488 | 200 µg/ml | $364.00 | |||
Orc2 Antibody (C-5) Alexa Fluor® 546 | sc-398410 AF546 | 200 µg/ml | $364.00 | |||
Orc2 Antibody (C-5) Alexa Fluor® 594 | sc-398410 AF594 | 200 µg/ml | $364.00 | |||
Orc2 Antibody (C-5) Alexa Fluor® 647 | sc-398410 AF647 | 200 µg/ml | $364.00 | |||
Orc2 Antibody (C-5) Alexa Fluor® 680 | sc-398410 AF680 | 200 µg/ml | $364.00 | |||
Orc2 Antibody (C-5) Alexa Fluor® 790 | sc-398410 AF790 | 200 µg/ml | $364.00 | |||
Orc2 (C-5) Neutralizing Peptide | sc-398410 P | 100 µg/0.5 ml | $69.00 |