OR5AU1 Antibody (F-10): sc-398756
- OR5AU1 Antibody (F-10) is a mouse monoclonal IgG2a κ OR5AU1 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 58-74 within an extracellular domain of OR5AU1 of human origin
- OR5AU1 Antibody (F-10) is recommended for detection of OR5AU1 of human origin, Olfr221 of mouse origin and Olr1638 of rat origin by WB, IP, IF and ELISA
- Anti-OR5AU1 Antibody (F-10) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for OR5AU1 Antibody (F-10) for WB applications. These reagents are now offered in bundles with OR5AU1 Antibody (F-10) (see ordering information below).
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OR5AU1 Antibody (F-10) is a mouse monoclonal IgG2a kappa light chain antibody that detects OR5AU1 in human, mouse, and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). OR5AU1 (F-10) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. OR5AU1, also known as olfactory receptor 5AU1 or OR14-38, is a multi-pass membrane protein consisting of 362 amino acids and belongs to the G-protein coupled receptor 1 family. OR5AU1 plays a crucial role in the olfactory system by interacting with odorant molecules, which initiates a neuronal response leading to the perception of smell. The olfactory receptor gene family, which includes OR5AU1, is the largest gene family in the human genome, highlighting the complexity and importance of olfactory signaling. The gene encoding OR5AU1 is located on chromosome 14q11.2, a region that houses over 700 genes and is implicated in various genetic disorders, including Alzheimer′s disease and α1-antitrypsin deficiency. Understanding OR5AU1 function and interactions with odorants is vital for elucidating the mechanisms of olfaction and its impact on behavior and health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
OR5AU1 Antibody (F-10) References:
- Genetic linkage evidence for a familial Alzheimer's disease locus on chromosome 14. | Schellenberg, GD., et al. 1992. Science. 258: 668-71. PMID: 1411576
- The human olfactory receptor gene family. | Malnic, B., et al. 2004. Proc Natl Acad Sci U S A. 101: 2584-9. PMID: 14983052
- Linkage to chromosome 14q in Alzheimer's disease (AD) patients without psychotic symptoms. | Avramopoulos, D., et al. 2005. Am J Med Genet B Neuropsychiatr Genet. 132B: 9-13. PMID: 15389761
- Genotype-phenotype relationships of presenilin-1 mutations in Alzheimer's disease: an update. | Larner, AJ. and Doran, M. 2009. J Alzheimers Dis. 17: 259-65. PMID: 19221408
- Alpha-1-antitrypsin phenotypes in adult liver disease patients. | Topic, A., et al. 2009. Ups J Med Sci. 114: 228-34. PMID: 19961268
- Rearrangement of the gene for the beta chain of the T-cell receptor in T-cell chronic lymphocytic leukemia and related disorders. | Aisenberg, AC., et al. 1985. N Engl J Med. 313: 529-33. PMID: 2862584
- Inversion of chromosome 14 marks human T-cell chronic lymphocytic leukaemia. | Zech, L., et al. Nature. 308: 858-60. PMID: 6609313
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
OR5AU1 Antibody (F-10) | sc-398756 | 200 µg/ml | $322.00 | |||
OR5AU1 Antibody (F-10): m-IgG Fc BP-HRP Bundle | sc-530918 | 200 µg Ab; 10 µg BP | $361.00 | |||
OR5AU1 Antibody (F-10): m-IgGκ BP-HRP Bundle | sc-524472 | 200 µg Ab, 40 µg BP | $361.00 | |||
OR5AU1 Antibody (F-10): m-IgG2a BP-HRP Bundle | sc-547630 | 200 µg Ab; 10 µg BP | $361.00 | |||
OR5AU1 Antibody (F-10) AC | sc-398756 AC | 500 µg/ml, 25% agarose | $424.00 | |||
OR5AU1 Antibody (F-10) HRP | sc-398756 HRP | 200 µg/ml | $322.00 | |||
OR5AU1 Antibody (F-10) FITC | sc-398756 FITC | 200 µg/ml | $336.00 | |||
OR5AU1 Antibody (F-10) PE | sc-398756 PE | 200 µg/ml | $349.00 | |||
OR5AU1 Antibody (F-10) Alexa Fluor® 488 | sc-398756 AF488 | 200 µg/ml | $364.00 | |||
OR5AU1 Antibody (F-10) Alexa Fluor® 546 | sc-398756 AF546 | 200 µg/ml | $364.00 | |||
OR5AU1 Antibody (F-10) Alexa Fluor® 594 | sc-398756 AF594 | 200 µg/ml | $364.00 | |||
OR5AU1 Antibody (F-10) Alexa Fluor® 647 | sc-398756 AF647 | 200 µg/ml | $364.00 | |||
OR5AU1 Antibody (F-10) Alexa Fluor® 680 | sc-398756 AF680 | 200 µg/ml | $364.00 | |||
OR5AU1 Antibody (F-10) Alexa Fluor® 790 | sc-398756 AF790 | 200 µg/ml | $364.00 | |||
OR5AU1 (F-10) Neutralizing Peptide | sc-398756 P | 100 µg/0.5 ml | $69.00 |