OCTL1 Antibody (B-5): sc-390931
- OCTL1 Antibody (B-5) is a mouse monoclonal IgG2a κ OCTL1 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 307-328 within a cytoplasmic domain of OCTL1 of human origin
- OCTL1 Antibody (B-5) is recommended for detection of OCTL1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
- Anti-OCTL1 Antibody (B-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for OCTL1 Antibody (B-5) for WB applications. These reagents are now offered in bundles with OCTL1 Antibody (B-5) (see ordering information below).
OCTL1 Antibody (B-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects OCTL1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). OCTL1 (B-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. OCTL1 protein, also known as SLC22A13, OCTL3, or ORCTL3, is a crucial member of the major facilitator superfamily and plays a significant role in the transport of organic cations, including catecholamines and neurotoxic compounds. This 551 amino acid transmembrane protein is predominantly expressed in glial cells and kidney tissue, highlighting OCTL1′s importance in the uptake and regulation of neurotransmitters and drugs within the central nervous system and renal system. OCTL1′s ability to facilitate the transport of organic cations is vital for drug absorption, targeting, and deposition, making OCTL1 a key player in pharmacokinetics and toxicology. Understanding OCTL1 function is essential for developing therapeutic strategies that optimize drug delivery and minimize neurotoxicity, thereby enhancing treatment efficacy and safety in clinical settings.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
OCTL1 Antibody (B-5) References:
- Cloning and characterization of a novel gene (C8orf2), a human representative of a novel gene family with homology to C. elegans C42.C1.9. | Ikegawa, S., et al. 1999. Cytogenet Cell Genet. 85: 227-31. PMID: 10449903
- Analysis of the gene structure of the human (SLC22A3) and murine (Slc22a3) extraneuronal monoamine transporter. | Wieland, A., et al. 2000. J Neural Transm (Vienna). 107: 1149-57. PMID: 11129104
- The localisation of the extraneuronal monoamine transporter (EMT) in rat brain. | Haag, C., et al. 2004. J Neurochem. 88: 291-7. PMID: 14690517
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | Gerhard, DS., et al. 2004. Genome Res. 14: 2121-7. PMID: 15489334
- Effect of splice-site polymorphisms of the TMPRSS4, NPHP4 and ORCTL4 genes on their mRNA expression. | Yamada, H., et al. 2005. J Genet. 84: 131-6. PMID: 16131712
- Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13). | Bahn, A., et al. 2008. J Biol Chem. 283: 16332-41. PMID: 18411268
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
OCTL1 Antibody (B-5) | sc-390931 | 200 µg/ml | $322.00 | |||
OCTL1 Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-530307 | 200 µg Ab; 10 µg BP | $361.00 | |||
OCTL1 Antibody (B-5): m-IgGκ BP-HRP Bundle | sc-523740 | 200 µg Ab, 40 µg BP | $361.00 | |||
OCTL1 Antibody (B-5): m-IgG2a BP-HRP Bundle | sc-547479 | 200 µg Ab; 10 µg BP | $361.00 | |||
OCTL1 Antibody (B-5) AC | sc-390931 AC | 500 µg/ml, 25% agarose | $424.00 | |||
OCTL1 Antibody (B-5) HRP | sc-390931 HRP | 200 µg/ml | $322.00 | |||
OCTL1 Antibody (B-5) FITC | sc-390931 FITC | 200 µg/ml | $336.00 | |||
OCTL1 Antibody (B-5) PE | sc-390931 PE | 200 µg/ml | $349.00 | |||
OCTL1 Antibody (B-5) Alexa Fluor® 488 | sc-390931 AF488 | 200 µg/ml | $364.00 | |||
OCTL1 Antibody (B-5) Alexa Fluor® 546 | sc-390931 AF546 | 200 µg/ml | $364.00 | |||
OCTL1 Antibody (B-5) Alexa Fluor® 594 | sc-390931 AF594 | 200 µg/ml | $364.00 | |||
OCTL1 Antibody (B-5) Alexa Fluor® 647 | sc-390931 AF647 | 200 µg/ml | $364.00 | |||
OCTL1 Antibody (B-5) Alexa Fluor® 680 | sc-390931 AF680 | 200 µg/ml | $364.00 | |||
OCTL1 Antibody (B-5) Alexa Fluor® 790 | sc-390931 AF790 | 200 µg/ml | $364.00 | |||
OCTL1 (B-5) Neutralizing Peptide | sc-390931 P | 100 µg/0.5 ml | $69.00 |