Oct3/4 Antibody (F-7): sc-514295
- Oct3/4 Antibody (F-7) is a mouse monoclonal IgG2b κ, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 331-360 at the C-terminus of Oct-3/4 of human origin
- recommended for detection of Oct-3/4 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-514295 X, 200 µg/0.1 ml)
- See Oct3/4 (C-10): sc-5279 for Oct3/4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Oct3/4 Antibody (F-7) for WB applications. These reagents are now offered in bundles with Oct3/4 Antibody (F-7) (see ordering information below).
Oct-3/4 Antibody (F-7) is a mouse monoclonal IgG2b antibody that detects Oct-3/4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Oct-3/4, also known as POU domain, class 5, transcription factor 1, plays a crucial role in maintaining the pluripotency and self-renewal of embryonic stem cells, making Oct-3/4 essential for early development and tissue differentiation. Oct-3/4 (F-7) antibody recognizes the protein primarily in the nucleus, where Oct-3/4 binds to specific DNA sequences to regulate the expression of genes involved in stem cell maintenance and differentiation. This nuclear localization allows Oct-3/4 to exert influence on gene transcription, thereby controlling the fate of stem cells and their ability to differentiate into various cell types. Oct-3/4 interacts with other transcription factors and co-regulators, which further modulates Oct-3/4 activity and impacts cellular processes. Expression of Oct-3/4 in certain cancer cell lines highlights Oct-3/4′s potential role in tumorigenesis, as Oct-3/4 can promote rapid cell proliferation and contribute to the undifferentiated state of cancer cells. With significant implications in developmental biology and cancer research, anti-Oct-3/4 antibody (F-7) serves as an invaluable tool for scientists studying stem cell dynamics and related pathways.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oct3/4 Antibody (F-7) | sc-514295 | 200 µg/ml | $322.00 | |||
Oct3/4 Antibody (F-7): m-IgGκ BP-HRP Bundle | sc-536262 | 200 µg Ab; 40 µg BP | $361.00 | |||
Oct3/4 Antibody (F-7): m-IgG2b BP-HRP Bundle | sc-549529 | 200 µg Ab; 10 µg BP | $361.00 | |||
Oct3/4 (F-7) Neutralizing Peptide | sc-514295 P | 100 µg/0.5 ml | $69.00 | |||
Oct3/4 Antibody (F-7) X | sc-514295 X | 200 µg/0.1 ml | $322.00 |