Oct-2 Antibody (F-5): sc-377475
- Oct-2 Antibody (F-5) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 435-463 at the C-terminus of Oct-2 of human origin
- recommended for detection of Oct-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including canine
- TransCruz reagent for ChIP application (sc-377475 X, 200 µg/0.1 ml)
- See Oct-2 (PT2): sc-56822 for Oct-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Oct-2 Antibody (F-5) for WB and IHC(P) applications. These reagents are now offered in bundles with Oct-2 Antibody (F-5) (see ordering information below).
Oct-2 Antibody (F-5) is a mouse monoclonal IgG1 antibody that detects Oct-2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Oct-2 plays a crucial role in the regulation of gene expression, particularly in the immune system, where Oct-2 is essential for the activation of immunoglobulin gene transcription in B cells. Oct-2 is primarily located in the nucleus, where Oct-2 binds to specific DNA sequences known as octamer motifs, which are vital for the transcription of immunoglobulin genes. Nuclear localization of Oct-2 allows for precise regulation of gene expression in response to cellular signals, ensuring that B cells can produce antibodies effectively during immune responses. Additionally, Oct-2 interacts with other transcription factors and coactivators, such as Oct-1 and OBF1, to form a complex that enhances the transcriptional activity of immunoglobulin promoters, thereby facilitating the production of antibodies necessary for adaptive immunity. Anti-Oct-2 antibody (F-5) is an invaluable tool for researchers studying B cell biology and the mechanisms of immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oct-2 Antibody (F-5) | sc-377475 | 200 µg/ml | $316.00 | |||
Oct-2 Antibody (F-5): m-IgG Fc BP-HRP Bundle | sc-540726 | 200 µg Ab; 10 µg BP | $354.00 | |||
Oct-2 Antibody (F-5): m-IgG1 BP-HRP Bundle | sc-542327 | 200 µg Ab; 20 µg BP | $354.00 | |||
Oct-2 (F-5) Neutralizing Peptide | sc-377475 P | 100 µg/0.5 ml | $68.00 | |||
Oct-2 Antibody (F-5) X | sc-377475 X | 200 µg/0.1 ml | $316.00 |