Date published: 2025-11-21

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Oct-2 Antibody (D-12): sc-365116

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Datasheets
  • Oct-2 Antibody (D-12) is a mouse monoclonal IgM κ, cited in 2 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 435-463 at the C-terminus of Oct-2 of human origin
  • recommended for detection of Oct-2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
  • TransCruz reagent for ChIP application (sc-365116 X, 200 µg/0.1 ml)
  • See Oct-2 (PT2): sc-56822 for Oct-2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Oct-2 Antibody (D-12). This work is in progress.

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SEE ALSO...

Oct-2 Antibody (D-12) is a mouse monoclonal IgM antibody that detects Oct-2 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Oct-2 (D-12) antibody plays a crucial role in studying the regulation of gene expression, particularly in the immune system, where Oct-2 is essential for activating immunoglobulin gene transcription in B cells. Oct-2 is primarily located in the nucleus, where Oct-2 binds to specific DNA sequences known as octamer motifs, which are vital for transcribing immunoglobulin genes and other tissue-specific genes. Oct-2′s interaction with various transcriptional coactivators, such as OBF1, enhances regulatory capacity, making Oct-2 a key player in B lymphocyte differentiation and function. Understanding Oct-2′s function and localization is important for elucidating immune response mechanisms and B cell-related disorders. Oct-2 (D-12) monoclonal antibody serves as an invaluable tool for researchers studying these processes and the broader implications of transcriptional regulation in health and disease.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oct-2 Antibody (D-12)

sc-365116
200 µg/ml
$316.00

Oct-2 (D-12) Neutralizing Peptide

sc-365116 P
100 µg/0.5 ml
$68.00

Oct-2 Antibody (D-12) X

sc-365116 X
200 µg/0.1 ml
$316.00

Could I please ask which specific kappa chain makes up this antibody? It seems that only VκI light chains can be immunoprecipitated by protein L beads. Thank you!

Asked by: Michael_Lee
Thank you for your question. I can confirm that this antibody has a kappa light chain. I do not have further information on which specific kappa chain it is. If you have any further questions, please contact Technical Service or reach out to your local distributor.
Answered by: Tech Service
Date published: 2019-11-25

What application is the blocking peptide sc-365116 P appropriate for?

Asked by: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-28
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Rated 5 out of 5 by from OCT2 antibodyExcellent antibody for both human and rat renal tissues. I used it for western blot.
Date published: 2019-06-07
Rated 5 out of 5 by from Good antibody for westernGood antibody for western, clean background and specific band in Ramos and Raji whole cell lysates. -SCBT QC
Date published: 2015-04-10
Rated 5 out of 5 by from Works well for IF applicationsWorks well for IF applications, positive in HeLa. -SCBT QC
Date published: 2015-02-03
Rated 5 out of 5 by from Good antibody for westernGood antibody for western, specific band in Raji whole cell lysate. -SCBT QC
Date published: 2015-01-22
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Oct-2 Antibody (D-12) is rated 5.0 out of 5 by 4.
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