Ob Antibody (B-4): sc-28344

Ob Antibody (B-4) is a mouse monoclonal IgG2a antibody that detects Ob in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Ob, also known as leptin, plays a crucial role in regulating energy balance by inhibiting hunger, which in turn helps to manage body weight. Ob is primarily secreted by adipose (fat) tissue and acts on the hypothalamus in the brain to signal satiety, making Ob a key player in the complex network of appetite regulation and energy homeostasis. Leptin′s importance extends beyond mere appetite control; Ob also influences various physiological processes, including metabolism and immune function. Notably, mutations in the Ob gene can lead to severe obesity and metabolic disorders, highlighting Ob′s critical role in maintaining healthy body weight and overall metabolic health. anti-Ob antibody (B-4) is designed to facilitate research into these vital functions and the underlying mechanisms of obesity, providing valuable insights into potential therapeutic targets for obesity-related conditions.

The preferred Ob antibody is Ob Antibody (F-3): sc-48408.