Date published: 2026-1-26

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Ob Inhibitors

Common Ob Inhibitors include, but are not limited to Piroxicam CAS 36322-90-4, Sodium 1-naphthalenesulfonate CAS 130-14-3, Curcumin CAS 458-37-7, Quercetin CAS 117-39-5 and Suramin sodium CAS 129-46-4.

Ob inhibitors refer to a distinct class of compounds that are designed to interact with and modulate the function of the hormone leptin, also known as "obesity factor" (Ob). Leptin is a protein hormone primarily secreted by adipose tissue, and it plays a pivotal role in regulating energy balance and body weight. The hormone exerts its effects by binding to specific receptors in the hypothalamus and other tissues, thereby influencing various physiological processes related to appetite, metabolism, and energy expenditure.

Ob inhibitors are tailored to target and disrupt the interactions between leptin and its receptors, affecting the downstream signaling pathways involved in energy homeostasis. By perturbing these interactions, researchers aim to gain insights into the intricate mechanisms underlying obesity and related metabolic disorders. These inhibitors provide a valuable tool for understanding the complexities of leptin signaling and its broader implications for the regulation of body weight and metabolism. Investigating the effects of Ob inhibitors sheds light on the interplay between leptin, the central nervous system, and peripheral tissues, thereby contributing to the broader understanding of how hormonal signals orchestrate the delicate balance between energy intake and expenditure.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Piroxicam

36322-90-4sc-200576
sc-200576A
1 g
5 g
$109.00
$376.00
2
(0)

Piroxicam is a non-steroidal anti-inflammatory drug (NSAID) that might impact OB-fold proteins involved in inflammation, potentially affecting their interactions and functions.

Sodium 1-naphthalenesulfonate

130-14-3sc-229291
sc-229291A
5 g
25 g
$32.00
$72.00
(1)

Naphthalene sulfonates are small molecules that might interact with OB-fold proteins, affecting their binding interactions and functions.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin might interact with OB-fold-containing proteins, influencing their ligand or nucleic acid binding activities and potential cellular functions.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid that might interact with OB-fold proteins, potentially affecting their binding activities and cellular roles.

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$152.00
$214.00
$728.00
$2601.00
$10965.00
$21838.00
$41096.00
5
(1)

Suramin is a polyanionic compound that might interact with OB-fold proteins, potentially influencing their interactions and cellular functions.

Proflavine hemisulfate salt

1811-28-5sc-215749
sc-215749A
10 g
25 g
$37.00
$112.00
(0)

Proflavine is a small molecule that might interact with OB-fold-containing proteins, potentially affecting their binding activities and functions.

Tetracycline

60-54-8sc-205858
sc-205858A
sc-205858B
sc-205858C
sc-205858D
10 g
25 g
100 g
500 g
1 kg
$63.00
$94.00
$270.00
$417.00
$634.00
6
(1)

Tetracycline antibiotics might interact with OB-fold proteins, potentially influencing their ligand or nucleic acid binding activities.

Fludarabine

21679-14-1sc-204755
sc-204755A
5 mg
25 mg
$58.00
$204.00
15
(1)

Fludarabine is a nucleoside analog that might interact with OB-fold-containing proteins, influencing their binding activities and functions.