NUDT7 Antibody (E-9): sc-390911
- NUDT7 Antibody (E-9) is a mouse monoclonal IgG1 κ NUDT7 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-28 at the N-terminus of NUDT7 of human origin
- NUDT7 Antibody (E-9) is recommended for detection of NUDT7 of human origin by WB, IP, IF and ELISA
- Anti-NUDT7 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NUDT7 Antibody (E-9) for WB applications. These reagents are now offered in bundles with NUDT7 Antibody (E-9) (see ordering information below).
NUDT7 Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects NUDT7 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). NUDT7 (E-9) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NUDT7, also known as nucleoside diphosphate-linked moiety X motif 7, is a 238 amino acid protein that plays a crucial role as a coenzyme A diphosphatase, facilitating the cleavage of coenzyme A into 3′,5′-ADP and 4′-phosphopantetheine, which is vital for various metabolic processes. NUDT7 is localized to the peroxisome, an organelle responsible for lipid metabolism and the detoxification of reactive oxygen species, highlighting NUDT7′s importance in maintaining cellular homeostasis. NUDT7 belongs to the nudix hydrolase family and the PCD1 subfamily, and shows expression in several human tissues, including the heart, spleen, liver, pancreas, pituitary, small intestine, kidney, and placenta. NUDT7 gene is located on human chromosome 16, which harbors over 900 genes and is implicated in various genetic disorders, including giant axonal neuropathy and Rubinstein-Taybi syndrome. Research on NUDT7 and related interactions remains essential for understanding cellular metabolism and potential implications in disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
NUDT7 Antibody (E-9) References:
- The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. | Bomont, P., et al. 2000. Nat Genet. 26: 370-4. PMID: 11062483
- The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives. | Gasmi, L. and McLennan, AG. 2001. Biochem J. 357: 33-8. PMID: 11415433
- Giant axonal neuropathy (GAN): case report and two novel mutations in the gigaxonin gene. | Kuhlenbäumer, G., et al. 2002. Neurology. 58: 1273-6. PMID: 11971098
- Genetics of inflammatory bowel disease: progress and prospects. | Mathew, CG. and Lewis, CM. 2004. Hum Mol Genet. 13 Spec No 1: R161-8. PMID: 14764625
- Advances in the genetics of inflammatory bowel disease. | Cho, JH. 2004. Curr Gastroenterol Rep. 6: 467-73. PMID: 15527676
- The Rubinstein-Taybi syndrome: occurrence in two sets of identical twins. | Baraitser, M. and Preece, MA. 1983. Clin Genet. 23: 318-20. PMID: 6682729
- Rubinstein-Taybi syndrome caused by submicroscopic deletions within 16p13.3. | Breuning, MH., et al. 1993. Am J Hum Genet. 52: 249-54. PMID: 8430691
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NUDT7 Antibody (E-9) | sc-390911 | 200 µg/ml | $316.00 | |||
NUDT7 Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-530299 | 200 µg Ab; 10 µg BP | $354.00 | |||
NUDT7 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-523730 | 200 µg Ab, 40 µg BP | $354.00 | |||
NUDT7 Antibody (E-9): m-IgG1 BP-HRP Bundle | sc-543980 | 200 µg Ab; 20 µg BP | $354.00 | |||
NUDT7 Antibody (E-9) AC | sc-390911 AC | 500 µg/ml, 25% agarose | $416.00 | |||
NUDT7 Antibody (E-9) HRP | sc-390911 HRP | 200 µg/ml | $316.00 | |||
NUDT7 Antibody (E-9) FITC | sc-390911 FITC | 200 µg/ml | $330.00 | |||
NUDT7 Antibody (E-9) PE | sc-390911 PE | 200 µg/ml | $343.00 | |||
NUDT7 Antibody (E-9) Alexa Fluor® 488 | sc-390911 AF488 | 200 µg/ml | $357.00 | |||
NUDT7 Antibody (E-9) Alexa Fluor® 546 | sc-390911 AF546 | 200 µg/ml | $357.00 | |||
NUDT7 Antibody (E-9) Alexa Fluor® 594 | sc-390911 AF594 | 200 µg/ml | $357.00 | |||
NUDT7 Antibody (E-9) Alexa Fluor® 647 | sc-390911 AF647 | 200 µg/ml | $357.00 | |||
NUDT7 Antibody (E-9) Alexa Fluor® 680 | sc-390911 AF680 | 200 µg/ml | $357.00 | |||
NUDT7 Antibody (E-9) Alexa Fluor® 790 | sc-390911 AF790 | 200 µg/ml | $357.00 | |||
NUDT7 (E-9) Neutralizing Peptide | sc-390911 P | 100 µg/0.5 ml | $68.00 |