NUDT10 Antibody (4B7): sc-100571
- NUDT10 Antibody (4B7) is a mouse monoclonal IgG2b κ provided at 100 µg/ml
- raised against recombinant NUDT10 of human origin
- recommended for detection of NUDT10 of mouse, rat and human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for NUDT10 Antibody (4B7). This work is in progress.
NUDT10 Antibody (4B7) is a mouse monoclonal IgG2b light chain antibody that detects NUDT10 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). NUDT10, also known as APS2 or DIPP3α, is a crucial member of the Nudix hydrolase family, which plays a significant role in cellular metabolism by hydrolyzing nucleoside diphosphate derivatives. NUDT10 functions as a manganese-dependent polyphosphate phosphohydrolase, with optimal activity at pH 8.5, and is particularly important for metabolizing diadendosine-polyphosphates and diphosphoinositol polyphosphates. NUDT10 localizes in the cytoplasm and is predominantly expressed in brain and liver tissues, while also found in prostate, testis, ovary, kidney, pancreas, placenta, spleen, lung, and heart, indicating widespread importance in various physiological processes. NUDT10 is closely related to NUDT11, differing by only a single amino acid, which highlights evolutionary conservation of function. Anti-NUDT10 antibody (4B7) serves as an essential tool for researchers studying the intricate roles of this protein in cellular signaling and metabolism.
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NUDT10 Antibody (4B7) References:
- Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases. | Hua, LV., et al. 2003. Biochem J. 373: 81-9. PMID: 12689335
- NUDT11 rs5945572 polymorphism and prostate cancer risk: a meta-analysis. | Li, W. and Gu, M. 2015. Int J Clin Exp Med. 8: 3474-81. PMID: 26064238
- Suggestive association between variants in IL1RAPL and asthma symptoms in Latin American children. | Marques, CR., et al. 2017. Eur J Hum Genet. 25: 439-445. PMID: 28120837
- Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression. | Kamdar, S., et al. 2019. Clin Epigenetics. 11: 54. PMID: 30917865
- Bioinformatics Analysis Reveals an Association Between Cancer Cell Stemness, Gene Mutations, and the Immune Microenvironment in Stomach Adenocarcinoma. | Ye, Z., et al. 2020. Front Genet. 11: 595477. PMID: 33362856
- Clinical correlations and prognostic value of Nudix hydroxylase 10 in patients with gastric cancer. | Chen, D., et al. 2021. Bioengineered. 12: 9779-9789. PMID: 34696672
- m7G Methylation-Related Genes as Biomarkers for Predicting Overall Survival Outcomes for Hepatocellular Carcinoma. | Li, XY., et al. 2022. Front Bioeng Biotechnol. 10: 849756. PMID: 35620469
- Correlation evaluation between cancer microenvironment related genes and prognosis based on intelligent medical internet of things. | Ren, S., et al. 2023. Front Genet. 14: 1132242. PMID: 36845384
- A signature of five 7-methylguanosine-related genes is a prognostic marker for lung squamous cell carcinoma. | Liu, W., et al. 2023. J Thorac Dis. 15: 6265-6278. PMID: 38090319
- Clinicopathological and molecular characterization of astrocytoma. | Wu, X., et al. 2025. Front Mol Neurosci. 18: 1483833. PMID: 39963393
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NUDT10 Antibody (4B7) | sc-100571 | 100 µg/ml | $339.00 |