Date published: 2026-5-9

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NUDT10 Activators

NUDT10 activators encompass a range of compounds that contribute to the enzyme's functional enhancement through different biochemical pathways. Central to the action of NUDT10 are substrates like ADP-ribose, 8-oxo-dGTP, GDP-mannose, and ADP-glucose, which upon hydrolysis, play crucial roles in maintaining cellular homeostasis. The hydrolysis of ADP-ribose by NUDT10, for instance, is integral to regulating energy metabolism and DNA repair processes, whereas the hydrolysis of 8-oxo-dGTP prevents its misincorporation into DNA, thereby safeguarding genomic stability. GDP-mannose and ADP-glucose, by serving as substrates, link NUDT10's activity to carbohydrate metabolism and glycogen synthesis, respectively.

Additionally, the presence of nucleotide cofactors and energy transfer molecules such as FAD, NADP+, NAD+, UTP, GTP, dATP, and CTP further enhances NUDT10's functionality. These compounds, through their roles in redox reactions, energy transfer, and nucleotide synthesis, indirectly modulate NUDT10 activity.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Adenosine-5′-diphosphoglucose disodium salt

102129-65-7sc-214509
sc-214509A
sc-214509B
sc-214509C
10 mg
25 mg
100 mg
250 mg
$110.00
$266.00
$693.00
$2228.00
(1)

ADP-glucose, involved in glycogen synthesis, could enhance NUDT10 activity by serving as a substrate for nucleotide hydrolysis.

β-Nicotinamide adenine dinucleotide phosphate

53-59-8sc-215560
sc-215560A
100 mg
250 mg
$182.00
$319.00
(1)

NADP+, a cofactor in anabolic reactions, can indirectly affect NUDT10 by influencing nucleotide metabolism and redox balance.

NAD+, Free Acid

53-84-9sc-208084B
sc-208084
sc-208084A
sc-208084C
sc-208084D
sc-208084E
sc-208084F
1 g
5 g
10 g
25 g
100 g
1 kg
5 kg
$57.00
$191.00
$302.00
$450.00
$1800.00
$3570.00
$10710.00
4
(2)

NAD+, involved in redox reactions, can impact NUDT10 activity indirectly through its role in energy metabolism and DNA repair pathways.

Uridine-5′-triphosphate, Trisodium Salt

19817-92-6sc-301964
sc-301964A
50 mg
1 g
$88.00
$120.00
2
(0)

UTP, a nucleotide involved in RNA synthesis, could be a substrate for NUDT10, influencing RNA metabolism and nucleotide pool balance.

Guanosine 5′-Triphosphate, Disodium Salt

56001-37-7sc-295030
sc-295030A
50 mg
250 mg
$166.00
$327.00
(1)

GTP, a key energy transfer molecule, can enhance NUDT10 activity by serving as a substrate, influencing energy metabolism and signal transduction.

Coenzyme A

85-61-0 anhydroussc-211123
sc-211123A
sc-211123B
sc-211123C
10 mg
25 mg
100 mg
250 mg
$83.00
$135.00
$418.00
$801.00
1
(1)

Coenzyme A, essential in fatty acid metabolism, can indirectly affect NUDT10 activity by influencing metabolic pathways where NUDT10 is involved.