NUDT10 activators encompass a range of compounds that contribute to the enzyme's functional enhancement through different biochemical pathways. Central to the action of NUDT10 are substrates like ADP-ribose, 8-oxo-dGTP, GDP-mannose, and ADP-glucose, which upon hydrolysis, play crucial roles in maintaining cellular homeostasis. The hydrolysis of ADP-ribose by NUDT10, for instance, is integral to regulating energy metabolism and DNA repair processes, whereas the hydrolysis of 8-oxo-dGTP prevents its misincorporation into DNA, thereby safeguarding genomic stability. GDP-mannose and ADP-glucose, by serving as substrates, link NUDT10's activity to carbohydrate metabolism and glycogen synthesis, respectively.
Additionally, the presence of nucleotide cofactors and energy transfer molecules such as FAD, NADP+, NAD+, UTP, GTP, dATP, and CTP further enhances NUDT10's functionality. These compounds, through their roles in redox reactions, energy transfer, and nucleotide synthesis, indirectly modulate NUDT10 activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine-5′-diphosphoglucose disodium salt | 102129-65-7 | sc-214509 sc-214509A sc-214509B sc-214509C | 10 mg 25 mg 100 mg 250 mg | $110.00 $266.00 $693.00 $2228.00 | ||
ADP-glucose, involved in glycogen synthesis, could enhance NUDT10 activity by serving as a substrate for nucleotide hydrolysis. | ||||||
β-Nicotinamide adenine dinucleotide phosphate | 53-59-8 | sc-215560 sc-215560A | 100 mg 250 mg | $182.00 $319.00 | ||
NADP+, a cofactor in anabolic reactions, can indirectly affect NUDT10 by influencing nucleotide metabolism and redox balance. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+, involved in redox reactions, can impact NUDT10 activity indirectly through its role in energy metabolism and DNA repair pathways. | ||||||
Uridine-5′-triphosphate, Trisodium Salt | 19817-92-6 | sc-301964 sc-301964A | 50 mg 1 g | $88.00 $120.00 | 2 | |
UTP, a nucleotide involved in RNA synthesis, could be a substrate for NUDT10, influencing RNA metabolism and nucleotide pool balance. | ||||||
Guanosine 5′-Triphosphate, Disodium Salt | 56001-37-7 | sc-295030 sc-295030A | 50 mg 250 mg | $166.00 $327.00 | ||
GTP, a key energy transfer molecule, can enhance NUDT10 activity by serving as a substrate, influencing energy metabolism and signal transduction. | ||||||
Coenzyme A | 85-61-0 anhydrous | sc-211123 sc-211123A sc-211123B sc-211123C | 10 mg 25 mg 100 mg 250 mg | $83.00 $135.00 $418.00 $801.00 | 1 | |
Coenzyme A, essential in fatty acid metabolism, can indirectly affect NUDT10 activity by influencing metabolic pathways where NUDT10 is involved. | ||||||