Nrarp Antibody (C-12): sc-515015
- Nrarp Antibody (C-12) is a mouse monoclonal IgG1 κ Nrarp antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-61 mapping at the N-terminus of Nrarp of human origin
- Nrarp Antibody (C-12) is recommended for detection of Nrarp of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-Nrarp Antibody (C-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Nrarp Antibody (C-12) for WB applications. These reagents are now offered in bundles with Nrarp Antibody (C-12) (see ordering information below).
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Nrarp Antibody (C-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects Nrarp protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Nrarp antibody (C-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Nrarp protein, or NOTCH-regulated ankyrin repeat protein, consists of 114 amino acids and features two ankyrin repeats, which are critical for protein-protein interactions. This structural characteristic is essential as Nrarp interacts with various signaling pathways, particularly those related to the Notch signaling cascade, which is vital for cell differentiation and development. The gene encoding Nrarp is located on human chromosome 9, a region associated with several genetic disorders, including hereditary hemorrhagic telangiectasia and familial dysautonomia. Understanding Nrarp′s role and interactions can provide insights into developmental processes and potential therapeutic targets for diseases linked to aberrant Notch signaling.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Nrarp Antibody (C-12) References:
- DNA sequence and analysis of human chromosome 9. | Humphray, SJ., et al. 2004. Nature. 429: 369-74. PMID: 15164053
- BCR-ABL activates STAT3 via JAK and MEK pathways in human cells. | Coppo, P., et al. 2006. Br J Haematol. 134: 171-9. PMID: 16846476
- BCR and its mutants, the reciprocal t(9;22)-associated ABL/BCR fusion proteins, differentially regulate the cytoskeleton and cell motility. | Zheng, X., et al. 2006. BMC Cancer. 6: 262. PMID: 17090304
- Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia. | Fernandez-L, A., et al. 2007. Hum Mol Genet. 16: 1515-33. PMID: 17420163
- Phenotypic and cytogenetic spectrum of 9p trisomy. | Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
- Potential role of tubulin acetylation and microtubule-based protein trafficking in familial dysautonomia. | Gardiner, J., et al. 2007. Traffic. 8: 1145-9. PMID: 17605759
- Pulmonary vascular manifestations of hereditary hemorrhagic telangiectasia (rendu-osler disease). | Cottin, V., et al. 2007. Respiration. 74: 361-78. PMID: 17641482
- A humanized IKBKAP transgenic mouse models a tissue-specific human splicing defect. | Hims, MM., et al. 2007. Genomics. 90: 389-96. PMID: 17644305
- Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia. | Burmeister, T., et al. 2007. Haematologica. 92: 1699-702. PMID: 18055996
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Nrarp Antibody (C-12) | sc-515015 | 200 µg/ml | $322.00 | |||
Nrarp Antibody (C-12): m-IgG Fc BP-HRP Bundle | sc-527967 | 200 µg Ab; 10 µg BP | $361.00 | |||
Nrarp Antibody (C-12): m-IgG1 BP-HRP Bundle | sc-533340 | 200 µg Ab; 20 µg BP | $361.00 | |||
Nrarp Antibody (C-12) AC | sc-515015 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Nrarp Antibody (C-12) HRP | sc-515015 HRP | 200 µg/ml | $322.00 | |||
Nrarp Antibody (C-12) FITC | sc-515015 FITC | 200 µg/ml | $336.00 | |||
Nrarp Antibody (C-12) PE | sc-515015 PE | 200 µg/ml | $349.00 | |||
Nrarp Antibody (C-12) Alexa Fluor® 488 | sc-515015 AF488 | 200 µg/ml | $364.00 | |||
Nrarp Antibody (C-12) Alexa Fluor® 546 | sc-515015 AF546 | 200 µg/ml | $364.00 | |||
Nrarp Antibody (C-12) Alexa Fluor® 594 | sc-515015 AF594 | 200 µg/ml | $364.00 | |||
Nrarp Antibody (C-12) Alexa Fluor® 647 | sc-515015 AF647 | 200 µg/ml | $364.00 | |||
Nrarp Antibody (C-12) Alexa Fluor® 680 | sc-515015 AF680 | 200 µg/ml | $364.00 | |||
Nrarp Antibody (C-12) Alexa Fluor® 790 | sc-515015 AF790 | 200 µg/ml | $364.00 |