NRAGE Antibody (F-9): sc-393291
- NRAGE Antibody (F-9) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 28-57 near the N-terminus of NRAGE of human origin
- Anti-NRAGE Antibody (F-9) is recommended for detection of NRAGE of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine and porcine
- Anti-NRAGE Antibody (F-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for NRAGE Antibody (F-9) for WB applications. These reagents are now offered in bundles with NRAGE Antibody (F-9) (see ordering information below).
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SEE ALSO...
NRAGE Antibody (F-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects NRAGE in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-NRAGE antibody (F-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. NRAGE, a member of the neurotrophin receptor-interacting MAGE homolog family, plays a pivotal role in neuronal development and survival by binding to the p75 neurotrophin receptor. This interaction facilitates NRAGE translocation to the plasma membrane upon nerve growth factor binding, which is essential for mediating neurotrophic signaling. NRAGE′s ability to induce cell cycle arrest and promote apoptosis in sympathetic neuron precursor cells underscores NRAGE′s importance in regulating neuronal differentiation and maintaining neuronal health. NRAGE expression in the medulla oblongata during development and in motor neurons highlights NRAGE′s significance in the central nervous system. Structural similarities between NRAGE and the melanoma-associated antigen necdin suggest shared mechanisms in influencing cell cycle dynamics, further emphasizing NRAGE′s relevance in neurobiology and potential therapeutic applications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NRAGE Antibody (F-9) | sc-393291 | 200 µg/ml | $322.00 | |||
NRAGE Antibody (F-9): m-IgG Fc BP-HRP Bundle | sc-530420 | 200 µg Ab; 10 µg BP | $361.00 | |||
NRAGE Antibody (F-9): m-IgGκ BP-HRP Bundle | sc-523890 | 200 µg Ab, 40 µg BP | $361.00 | |||
NRAGE Antibody (F-9) AC | sc-393291 AC | 500 µg/ml, 25% agarose | $424.00 | |||
NRAGE Antibody (F-9) HRP | sc-393291 HRP | 200 µg/ml | $322.00 | |||
NRAGE Antibody (F-9) FITC | sc-393291 FITC | 200 µg/ml | $336.00 | |||
NRAGE Antibody (F-9) PE | sc-393291 PE | 200 µg/ml | $349.00 | |||
NRAGE Antibody (F-9) Alexa Fluor® 488 | sc-393291 AF488 | 200 µg/ml | $364.00 | |||
NRAGE Antibody (F-9) Alexa Fluor® 546 | sc-393291 AF546 | 200 µg/ml | $364.00 | |||
NRAGE Antibody (F-9) Alexa Fluor® 594 | sc-393291 AF594 | 200 µg/ml | $364.00 | |||
NRAGE Antibody (F-9) Alexa Fluor® 647 | sc-393291 AF647 | 200 µg/ml | $364.00 | |||
NRAGE Antibody (F-9) Alexa Fluor® 680 | sc-393291 AF680 | 200 µg/ml | $364.00 | |||
NRAGE Antibody (F-9) Alexa Fluor® 790 | sc-393291 AF790 | 200 µg/ml | $364.00 | |||
NRAGE (F-9) Neutralizing Peptide | sc-393291 P | 100 µg/0.5 ml | $69.00 |